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Found 20 Enz. Inhib. hit(s) with all data for entry = 50039892
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385902(CHEMBL2041596)
Affinity DataKi:  5.91E+3nMAssay Description:Competitive inhibition of human recombinant PDE7A1 using 5 nM to 2 uM cAMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385903(CHEMBL2041614)
Affinity DataKi:  7.22E+3nMAssay Description:Competitive inhibition of human recombinant PDE7A1 using 5 nM to 2 uM cAMP as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50277784(CHEMBL484928 | N,N,2-trimethyl-5-nitrobenzenesulfo...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385909(CHEMBL2041586)
Affinity DataIC50:  580nMAssay Description:Inhibition of PDE7A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM77437(1-({[5-(ethoxycarbonyl)-4-methyl-1,3-thiazol-2-yl]...)
Affinity DataIC50:  860nMAssay Description:Inhibition of PDE7A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385910(CHEMBL2041587)
Affinity DataIC50:  880nMAssay Description:Inhibition of PDE7A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385906(CHEMBL2041597)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385906(CHEMBL2041597)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385903(CHEMBL2041614)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385908(CHEMBL2041604)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385903(CHEMBL2041614)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385902(CHEMBL2041596)
Affinity DataIC50:  5.17E+3nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385907(CHEMBL2041602)
Affinity DataIC50:  7.31E+3nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385905(CHEMBL2041590)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385902(CHEMBL2041596)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of human recombinant PDE4B2 using fluorscein 3',5'-cyclic phosphate after 60 mins by IMAP fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385908(CHEMBL2041604)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385904(CHEMBL2041589)
Affinity DataIC50:  3.34E+4nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385902(CHEMBL2041596)
Affinity DataIC50:  5.46E+4nMAssay Description:Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385902(CHEMBL2041596)
Affinity DataIC50:  6.63E+4nMAssay Description:Inhibition of human recombinant PDE4D3 using fluorscein 3',5'-cyclic phosphate after 60 mins by IMAP fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50385905(CHEMBL2041590)
Affinity DataIC50:  1.04E+5nMAssay Description:Inhibition of human recombinant PDE3A-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed