Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50039553
TargetMetabotropic glutamate receptor 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379862(CHEMBL2011870)
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379866(CHEMBL2011874)
Affinity DataIC50: 7nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379867(CHEMBL2011877)
Affinity DataIC50: 7nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379861(CHEMBL2011876)
Affinity DataIC50: 9nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379865(CHEMBL2011873)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379862(CHEMBL2011870)
Affinity DataIC50: 32nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379862(CHEMBL2011870)
Affinity DataIC50: 32nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379868(CHEMBL2011878)
Affinity DataIC50: 39nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379864(CHEMBL2011872)
Affinity DataIC50: 65nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379869(CHEMBL2011879)
Affinity DataIC50: 67nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379865(CHEMBL2011873)
Affinity DataIC50: 92nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379860(CHEMBL2011875)
Affinity DataIC50: 100nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379863(CHEMBL2011871)
Affinity DataIC50: 110nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379870(CHEMBL2011880)
Affinity DataIC50: 138nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379862(CHEMBL2011870)
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379866(CHEMBL2011874)
Affinity DataIC50: 159nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379867(CHEMBL2011877)
Affinity DataIC50: 730nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379861(CHEMBL2011876)
Affinity DataIC50: 1.22E+3nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379868(CHEMBL2011878)
Affinity DataIC50: 6.65E+3nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379860(CHEMBL2011875)
Affinity DataIC50: 1.25E+4nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379864(CHEMBL2011872)
Affinity DataIC50: 1.25E+4nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379869(CHEMBL2011879)
Affinity DataIC50: 1.25E+4nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50379870(CHEMBL2011880)
Affinity DataIC50: 1.25E+4nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed