Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50039565
TargetDihydrofolate reductase(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 123nMAssay Description:Inhibition of DHFR using dihydrofolate as substrate following 3 mins substrate preincubation measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50380095(CHEMBL2012911)
Affinity DataIC50: 340nMAssay Description:Inhibition of DHFR using dihydrofolate as substrate following 3 mins substrate preincubation measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50380092(CHEMBL2012918)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DHFR using dihydrofolate as substrate following 3 mins substrate preincubation measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50380093(CHEMBL2012917)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of DHFR using dihydrofolate as substrate following 3 mins substrate preincubation measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50380094(CHEMBL2012914)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of DHFR using dihydrofolate as substrate following 3 mins substrate preincubation measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50380096(CHEMBL2012916)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of DHFR using dihydrofolate as substrate following 3 mins substrate preincubation measured after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed