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Found
19
Enz. Inhib. hit(s) with all data for entry = 50040095
Target
Serine/threonine-protein kinase PAK 4
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389112
(CHEMBL2064556)
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Copy InChI
Affinity Data
Ki: 2.80nM
Assay Description:
Inhibition of PAK4
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Cyclin-dependent kinase 2
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389111
(CHEMBL2064555)
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Copy InChI
Affinity Data
Ki: 3.40nM
Assay Description:
Inhibition of CDK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Serine/threonine-protein kinase PAK 4
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389111
(CHEMBL2064555)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6nM
Assay Description:
Inhibition of PAK4
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Serine/threonine-protein kinase PAK 4
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389116
(CHEMBL2064561)
Copy SMILES
Copy InChI
Affinity Data
Ki: 12nM
Assay Description:
Inhibition of PAK4
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Serine/threonine-protein kinase PAK 4
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389117
(CHEMBL2064562)
Copy SMILES
Copy InChI
Affinity Data
Ki: 13nM
Assay Description:
Inhibition of PAK4
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Serine/threonine-protein kinase PAK 4
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389113
(CHEMBL2064558)
Copy SMILES
Copy InChI
Affinity Data
Ki: 30nM
Assay Description:
Inhibition of PAK4
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Serine/threonine-protein kinase PAK 4
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389120
(CHEMBL2064565)
Copy SMILES
Copy InChI
Affinity Data
Ki: 31nM
Assay Description:
Inhibition of PAK4
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Serine/threonine-protein kinase PAK 4
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389109
(CHEMBL2064557)
Copy SMILES
Copy InChI
Affinity Data
Ki: 64nM
Assay Description:
Inhibition of PAK4
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
Serine/threonine-protein kinase PAK 4
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389119
(CHEMBL2064564)
Copy SMILES
Copy InChI
Affinity Data
Ki: 68nM
Assay Description:
Inhibition of PAK4
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Serine/threonine-protein kinase PAK 4
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389118
(CHEMBL2064563)
Copy SMILES
Copy InChI
Affinity Data
Ki: 98nM
Assay Description:
Inhibition of PAK4
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Serine/threonine-protein kinase MARK1
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389121
(CHEMBL2064628)
Copy SMILES
Copy InChI
Affinity Data
IC50: 115nM
Assay Description:
Inhibition of MARK1
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Mitogen-activated protein kinase 1
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389121
(CHEMBL2064628)
Copy SMILES
Copy InChI
Affinity Data
IC50: 170nM
Assay Description:
Inhibition of Erk2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Serine/threonine-protein kinase PAK 4
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389115
(CHEMBL2064560)
Copy SMILES
Copy InChI
Affinity Data
Ki: 207nM
Assay Description:
Inhibition of PAK4
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Glycogen synthase kinase-3 beta
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389121
(CHEMBL2064628)
Copy SMILES
Copy InChI
Affinity Data
IC50: 227nM
Assay Description:
Inhibition of GSK3beta
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Cyclin-dependent kinase 2
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389121
(CHEMBL2064628)
Copy SMILES
Copy InChI
Affinity Data
IC50: 450nM
Assay Description:
Inhibition of CDK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Serine/threonine-protein kinase PAK 4
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389114
(CHEMBL2064559)
Copy SMILES
Copy InChI
Affinity Data
Ki: 512nM
Assay Description:
Inhibition of PAK4
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Cyclin-dependent kinase 2
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389117
(CHEMBL2064562)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.16E+3nM
Assay Description:
Inhibition of CDK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Cyclin-dependent kinase 2
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389113
(CHEMBL2064558)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.80E+3nM
Assay Description:
Inhibition of CDK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Cyclin-dependent kinase 2
(Human)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389116
(CHEMBL2064561)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.00E+3nM
Assay Description:
Inhibition of CDK2
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
2/8/2013
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL