Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50039860
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50108653(1'-benzyl-3-methoxyspiro[3,4-dihydro-1H-isochromen...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302094(1'-butyl-3-methoxyspiro[isochroman-1,4'-piperidine...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385259(CHEMBL2035281)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385256(CHEMBL2034985)
Affinity DataKi:  9.40nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385257(CHEMBL2035279)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385261(CHEMBL2035278)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385251(CHEMBL2035283)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385253(CHEMBL2035275)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385254(CHEMBL2035276)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385258(CHEMBL2035280)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385252(CHEMBL2035274)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385255(CHEMBL2035277)
Affinity DataKi:  104nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302085(CHEMBL571152 | cis-1'-Butyl-3-methoxy-3,4-dihydros...)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302096(CHEMBL570272 | cis-1'-Benzyl-3-methoxy-3,4-dihydro...)
Affinity DataKi: >1.40E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385260(CHEMBL2035282)
Affinity DataKi:  1.52E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385253(CHEMBL2035275)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385254(CHEMBL2035276)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385259(CHEMBL2035281)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385252(CHEMBL2035274)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385251(CHEMBL2035283)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385257(CHEMBL2035279)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385261(CHEMBL2035278)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385256(CHEMBL2034985)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385255(CHEMBL2035277)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385254(CHEMBL2035276)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385253(CHEMBL2035275)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385252(CHEMBL2035274)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385260(CHEMBL2035282)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385251(CHEMBL2035283)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385259(CHEMBL2035281)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385258(CHEMBL2035280)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385257(CHEMBL2035279)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385261(CHEMBL2035278)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385256(CHEMBL2034985)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385260(CHEMBL2035282)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385258(CHEMBL2035280)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385255(CHEMBL2035277)
Affinity DataIC50: >100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed