Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50039860
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50108653(1'-benzyl-3-methoxyspiro[3,4-dihydro-1H-isochromen...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302094(1'-butyl-3-methoxyspiro[isochroman-1,4'-piperidine...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385259(CHEMBL2035281)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385256(CHEMBL2034985)
Affinity DataKi:  9.40nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385257(CHEMBL2035279)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385261(CHEMBL2035278)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385251(CHEMBL2035283)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385253(CHEMBL2035275)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50035131((1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-enyl)-...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385254(CHEMBL2035276)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385258(CHEMBL2035280)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | cid_7333 | Di-o-tolylguanidine | DIT...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385252(CHEMBL2035274)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385258(CHEMBL2035280)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385256(CHEMBL2034985)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385255(CHEMBL2035277)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385257(CHEMBL2035279)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385261(CHEMBL2035278)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385260(CHEMBL2035282)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385261(CHEMBL2035278)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385256(CHEMBL2034985)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385251(CHEMBL2035283)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385257(CHEMBL2035279)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385253(CHEMBL2035275)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385252(CHEMBL2035274)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385259(CHEMBL2035281)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385254(CHEMBL2035276)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385259(CHEMBL2035281)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385258(CHEMBL2035280)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385260(CHEMBL2035282)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT7 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385251(CHEMBL2035283)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385253(CHEMBL2035275)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385252(CHEMBL2035274)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385255(CHEMBL2035277)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385254(CHEMBL2035276)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5HT6 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385255(CHEMBL2035277)
Affinity DataKi:  104nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302085(cis-1'-Butyl-3-methoxy-3,4-dihydrospiro[[2]benzopy...)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50302096(cis-1'-Benzyl-3-methoxy-3,4-dihydrospiro[[2]benzop...)
Affinity DataKi: >1.40E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50385260(CHEMBL2035282)
Affinity DataKi:  1.52E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed