Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50039794
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384248BDBM50384248(CHEMBL2030451)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384249BDBM50384249(CHEMBL2030450)
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384250BDBM50384250(CHEMBL2030448)
Affinity DataIC50: 252nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384252BDBM50384252(CHEMBL2029359)
Affinity DataIC50: 262nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384253BDBM50384253(CHEMBL2030445)
Affinity DataIC50: 285nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384247BDBM50384247(CHEMBL2030436)
Affinity DataIC50: 288nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384251BDBM50384251(CHEMBL2030446)
Affinity DataIC50: 303nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384256BDBM50384256(CHEMBL2030447)
Affinity DataIC50: 385nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384248BDBM50384248(CHEMBL2030451)
Affinity DataIC50: 565nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384258BDBM50384258(CHEMBL2030443)
Affinity DataIC50: 601nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384252BDBM50384252(CHEMBL2029359)
Affinity DataIC50: 980nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384253BDBM50384253(CHEMBL2030445)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384261BDBM50384261(CHEMBL2030439)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384255BDBM50384255(CHEMBL1312643)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384254BDBM50384254(CHEMBL2030442)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384260BDBM50384260(CHEMBL2030438)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384258BDBM50384258(CHEMBL2030443)
Affinity DataIC50: 2.05E+3nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384245BDBM50384245(CHEMBL2030449)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384259BDBM50384259(CHEMBL2030437)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384262BDBM50384262(CHEMBL2030440)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384247BDBM50384247(CHEMBL2030436)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384256BDBM50384256(CHEMBL2030447)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384261BDBM50384261(CHEMBL2030439)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384254BDBM50384254(CHEMBL2030442)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384255BDBM50384255(CHEMBL1312643)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384257BDBM50384257(CHEMBL2030444)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384251BDBM50384251(CHEMBL2030446)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384246BDBM50384246(CHEMBL2030441)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384247BDBM50384247(CHEMBL2030436)
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384245BDBM50384245(CHEMBL2030449)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human ERG by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384252BDBM50384252(CHEMBL2029359)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERG by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384251BDBM50384251(CHEMBL2030446)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERG by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384253BDBM50384253(CHEMBL2030445)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERG by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384255BDBM50384255(CHEMBL1312643)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERG by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384247BDBM50384247(CHEMBL2030436)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERG by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384250BDBM50384250(CHEMBL2030448)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERG by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384254BDBM50384254(CHEMBL2030442)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERG by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384249BDBM50384249(CHEMBL2030450)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERG by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384260BDBM50384260(CHEMBL2030438)
Affinity DataIC50: 3.67E+4nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384250BDBM50384250(CHEMBL2030448)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384259BDBM50384259(CHEMBL2030437)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384246BDBM50384246(CHEMBL2030441)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384249BDBM50384249(CHEMBL2030450)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384245BDBM50384245(CHEMBL2030449)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384248BDBM50384248(CHEMBL2030451)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG by whole cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384257BDBM50384257(CHEMBL2030444)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384262BDBM50384262(CHEMBL2030440)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant PI3Kalpha expressed in baculovirus system using PI(4,5)P2 as substrate after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed