Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50040653
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50397835(CHEMBL2178521)
Affinity DataIC50:  1.80E+3nMAssay Description:Displacement of [3H]dofetilide to human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50397831(CHEMBL2151218)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [3H]dofetilide to human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50397830(CHEMBL2151164)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50397830(CHEMBL2151164)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50397830(CHEMBL2151164)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextrometorphan as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50397834(CHEMBL2178522)
Affinity DataIC50:  5.20E+3nMAssay Description:Displacement of [3H]dofetilide to human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50397830(CHEMBL2151164)
Affinity DataIC50:  8.50E+3nMAssay Description:Displacement of [3H]dofetilide to human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50397830(CHEMBL2151164)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50397833(CHEMBL2178523)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide to human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50397832(CHEMBL2178524)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide to human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50397830(CHEMBL2151164)
Affinity DataIC50:  2.19E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50397830(CHEMBL2151164)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed