Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50004776
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50485724(CHEMBL2159008)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 0.05 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50485727(CHEMBL2159009)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 0.05 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50485722(Ethidium Homodimer-1 | CHEMBL2159003)
Affinity DataIC50: 11nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 0.05 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50485725(CHEMBL2159010)
Affinity DataIC50: 11nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 0.05 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50485726(CHEMBL2159011)
Affinity DataIC50: 22nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 0.05 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50485728(CHEMBL2159012)
Affinity DataIC50: 31nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 0.05 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50485723(Acridine Dimer)
Affinity DataIC50: 220nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 0.05 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50485723(Acridine Dimer)
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 0.5 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM200295(Ethidium bromide | AB00053825_07 | cid_3624)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 0.5 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50105463(3,8-diamino-5-ethyl-6-phenylphenanthridinium bromi...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM200295(Ethidium bromide | AB00053825_07 | cid_3624)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 0.05 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM200295(Ethidium bromide | AB00053825_07 | cid_3624)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 25 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50485722(Ethidium Homodimer-1 | CHEMBL2159003)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 25 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50235326(CHEBI:51240 | Propidium | Propidium Iodide | Propi...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50485722(Ethidium Homodimer-1 | CHEMBL2159003)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 25 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assay in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50485723(Acridine Dimer)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 25 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM24709(CHEMBL94007 | 7-ethoxyacridine-3,9-diamine | 6,9-D...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50105464(2,7-Dimethyl-acridine-3,6-diamine | CHEMBL329221)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50485721(CHEBI:52304 | 7-Amino Actinomycin D | CHEMBL215900...)
Affinity DataIC50: 9.30E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50368352(Cerubidine | DAUNORUBICIN)
Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50004233(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | TCMDC-12...)
Affinity DataIC50: 1.82E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50105462(N,N,N',N'-Tetramethyl-acridine-3,6-diamine | CHEMB...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM50089528(Actinomycin D analogue | Actinomycin D | Cosmegen ...)
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed