Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50039972
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387062BDBM50387062(CHEMBL2047041)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387054BDBM50387054(CHEMBL2047033)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387062BDBM50387062(CHEMBL2047041)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387056BDBM50387056(CHEMBL2047034)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387057BDBM50387057(CHEMBL2047039)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387057BDBM50387057(CHEMBL2047039)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387064BDBM50387064(CHEMBL2047038)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387054BDBM50387054(CHEMBL2047033)
Affinity DataIC50: 14nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387056BDBM50387056(CHEMBL2047034)
Affinity DataIC50: 15nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387065BDBM50387065(CHEMBL2047037)
Affinity DataIC50: 16nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387064BDBM50387064(CHEMBL2047038)
Affinity DataIC50: 18nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387065BDBM50387065(CHEMBL2047037)
Affinity DataIC50: 49nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387053BDBM50387053(CHEMBL2047035)
Affinity DataIC50: 73nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387058BDBM50387058(CHEMBL2047045)
Affinity DataIC50: 78nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387058BDBM50387058(CHEMBL2047045)
Affinity DataIC50: 160nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387053BDBM50387053(CHEMBL2047035)
Affinity DataIC50: 180nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387060BDBM50387060(CHEMBL2047043)
Affinity DataIC50: 220nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387063BDBM50387063(CHEMBL2047040)
Affinity DataIC50: 260nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387055BDBM50387055(CHEMBL2047032)
Affinity DataIC50: 270nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387063BDBM50387063(CHEMBL2047040)
Affinity DataIC50: 400nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387060BDBM50387060(CHEMBL2047043)
Affinity DataIC50: 500nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387055BDBM50387055(CHEMBL2047032)
Affinity DataIC50: 560nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387059BDBM50387059(CHEMBL2047044)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387059BDBM50387059(CHEMBL2047044)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387052BDBM50387052(CHEMBL2047036)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387061BDBM50387061(CHEMBL2047042)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387061BDBM50387061(CHEMBL2047042)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) cells using Swedish mutant sequence Eu-EVNLDAEFK-quencher at 10 uM after 60 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Link£Ping University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387052BDBM50387052(CHEMBL2047036)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BACE1 expressed in human HEK293 cells expressing Swedish mutant APP assessed as reduction on amyloid beta (1 to 40) production after 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed