Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50040063
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of angiotensin AT1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388737(CHEMBL2058860)
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50043280(4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimi...)
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388736(CHEMBL2058859)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388737(CHEMBL2058860)
Affinity DataKd:  1.70nMAssay Description:Antagonist activity at AT1 receptor in Japanese white rabbit thoracic aorta assessed as inhibition of KCl-induced contraction incubated 30 mins post ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388741(CHEMBL2058864)
Affinity DataKd:  1.82nMAssay Description:Antagonist activity at AT1 receptor in Japanese white rabbit thoracic aorta assessed as inhibition of KCl-induced contraction incubated 30 mins post ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388738(CHEMBL2058861)
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388741(CHEMBL2058864)
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388736(CHEMBL2058859)
Affinity DataKd:  4.79nMAssay Description:Antagonist activity at AT1 receptor in Japanese white rabbit thoracic aorta assessed as inhibition of KCl-induced contraction incubated 30 mins post ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataKd:  12.6nMAssay Description:Antagonist activity at AT1 receptor in Japanese white rabbit thoracic aorta assessed as inhibition of KCl-induced contraction incubated 30 mins post ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388738(CHEMBL2058861)
Affinity DataKd:  14.8nMAssay Description:Antagonist activity at AT1 receptor in Japanese white rabbit thoracic aorta assessed as inhibition of KCl-induced contraction incubated 30 mins post ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataIC50: 16.2nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388732(CHEMBL2058855)
Affinity DataIC50: 19.7nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388739(CHEMBL2058862)
Affinity DataIC50: 22.5nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388730(CHEMBL2058865)
Affinity DataIC50: 37.6nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388740(CHEMBL2058863)
Affinity DataIC50: 78nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388733(CHEMBL2058856)
Affinity DataIC50: 78.3nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388735(CHEMBL2058858)
Affinity DataIC50: 96.8nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388734(CHEMBL2058857)
Affinity DataIC50: 119nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50043280(4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimi...)
Affinity DataIC50: 150nMAssay Description:Inhibition of angiotensin AT1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388742(CHEMBL2058866)
Affinity DataIC50: 209nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388731(CHEMBL2058588)
Affinity DataIC50: 410nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed