Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50040863
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401167(CHEMBL2205792)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human His10-tagged P-gp ATPase activity expressed in BHK cells assessed as verapamil-induced inorganic phosphate release incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401170(CHEMBL2205793)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human His10-tagged P-gp ATPase activity expressed in BHK cells assessed as verapamil-induced inorganic phosphate release incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401167(CHEMBL2205792)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as inhibition of [3H]vinblastine efflux incubated for 30 mins prior to [3H]vinblastine additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401172(CHEMBL2205790)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as increase in calcein AM uptake incubated for 30 mins prior to calcein AM influx measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401172(CHEMBL2205790)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as inhibition of [3H]vinblastine efflux incubated for 30 mins prior to [3H]vinblastine additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401171(CHEMBL2205791)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as inhibition of [3H]vinblastine efflux incubated for 30 mins prior to [3H]vinblastine additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401171(CHEMBL2205791)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as increase in calcein AM uptake incubated for 30 mins prior to calcein AM influx measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401170(CHEMBL2205793)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as inhibition of [3H]vinblastine efflux incubated for 30 mins prior to [3H]vinblastine additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401170(CHEMBL2205793)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as increase in calcein AM uptake incubated for 30 mins prior to calcein AM influx measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401169(CHEMBL2205788)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as increase in calcein AM uptake incubated for 30 mins prior to calcein AM influx measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401168(CHEMBL2205787)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as increase in calcein AM uptake incubated for 30 mins prior to calcein AM influx measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50249854(12-(Dimethylamino)-2,3,6,7-tetrahydro-9-(N-piperid...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as increase in calcein AM uptake incubated for 30 mins prior to calcein AM influx measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401167(CHEMBL2205792)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as increase in calcein AM uptake incubated for 30 mins prior to calcein AM influx measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401166(CHEMBL2205785)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as increase in calcein AM uptake incubated for 30 mins prior to calcein AM influx measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401165(CHEMBL2205789)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as increase in calcein AM uptake incubated for 30 mins prior to calcein AM influx measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401163(CHEMBL2205786)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as increase in calcein AM uptake incubated for 30 mins prior to calcein AM influx measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401164(CHEMBL493431)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as increase in calcein AM uptake incubated for 30 mins prior to calcein AM influx measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed