TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-epibatidine from human nAChR alpha4beta2 expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [3H]-epibatidine from human nAChR alpha4beta2 expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Displacement of [3H]-epibatidine from human nAChR alpha4beta2 expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Displacement of [3H]-epibatidine from human nAChR alpha4beta2 expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 560nMAssay Description:Binding affinity to human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Binding affinity to human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Binding affinity to human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Binding affinity to human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cellsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 6.90E+3nMAssay Description:Binding affinity to human nAChR alpha7 expressed in HEK cells coexpressing RIC3More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 7.60E+3nMAssay Description:Binding affinity to human nAChR alpha7 expressed in HEK cells coexpressing RIC3More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 7.90E+3nMAssay Description:Binding affinity to human nAChR alpha7 expressed in HEK cells coexpressing RIC3More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 8.00E+3nMAssay Description:Binding affinity to human nAChR alpha7 expressed in HEK cells coexpressing RIC3More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataEC50: 5.50E+4nMAssay Description:Antagonist activity at human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cells assessed as calcium flux by fluorescence analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataEC50: 3.10E+4nMAssay Description:Antagonist activity at human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cells assessed as calcium flux by fluorescence analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataEC50: 6.90E+3nMAssay Description:Antagonist activity at human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cells assessed as calcium flux by fluorescence analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataEC50: 2.60E+3nMAssay Description:Antagonist activity at human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cells assessed as calcium flux by fluorescence analysisMore data for this Ligand-Target Pair