Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50040865
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Groningen Research Institute of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 500nMAssay Description:Inhibition of 5-LOXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
Groningen Research Institute of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50401193(CHEMBL1934604)
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of soybean lipoxygenase-1 assessed as inhibition constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
Groningen Research Institute of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50401193(CHEMBL1934604)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of soybean lipoxygenase-1 assessed as formation of 13-HPOD from linolenic acid preincubated for 10 mins measured by real-time spectrophoto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
Groningen Research Institute of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50401193(CHEMBL1934604)
Affinity DataKi:  1.57E+4nMAssay Description:Inhibition of soybean lipoxygenase-1 assessed as inhibition constant for enzyme-substrate-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProbable linoleate 9S-lipoxygenase 5(Potato)
Groningen Research Institute of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50240436(2-hydroxy-6-pentadecylbenzoic acid | 6-(pentadecen...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of potato 5-lipoxygenase assessed as residual activity preincubated for 10 mins measured by real-time spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
Groningen Research Institute of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50240436(2-hydroxy-6-pentadecylbenzoic acid | 6-(pentadecen...)
Affinity DataIC50: 5.19E+4nMAssay Description:Inhibition of soybean lipoxygenase-1 assessed as formation of 13-HPOD from linolenic acid preincubated for 10 mins measured by real-time spectrophoto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
Groningen Research Institute of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50401192(CHEMBL418973)
Affinity DataIC50: 5.54E+4nMAssay Description:Inhibition of soybean lipoxygenase-1 assessed as formation of 13-HPOD from linolenic acid preincubated for 10 mins measured by real-time spectrophoto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
Groningen Research Institute of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50401191(CHEMBL2206368)
Affinity DataIC50: 5.85E+4nMAssay Description:Inhibition of soybean lipoxygenase-1 assessed as formation of 13-HPOD from linolenic acid preincubated for 10 mins measured by real-time spectrophoto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed