Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50022483
TargetCentromere-associated protein E(Human)
Children's Hospital of Philadelphia

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataIC50: 17nMAssay Description:Inhibition of CENP-E in human SW48 cells assessed as decrease in cell viability after 72 hrs by Cell-titer Glo reagent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Children's Hospital of Philadelphia

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataIC50: 42nMAssay Description:Inhibition of CENP-E in human SW620 cells expressing KRAS mutant assessed as decrease in cell viability after 72 hrs by Cell-titer Glo reagent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Children's Hospital of Philadelphia

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataIC50: 52nMAssay Description:Inhibition of CENP-E in human HCT-116 cells expressing KRAS mutant assessed as decrease in cell viability after 72 hrs by Cell-titer Glo reagent assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Children's Hospital of Philadelphia

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataIC50: 56nMAssay Description:Inhibition of CENP-E in human RKO cells expressing BRAF mutant assessed as decrease in cell viability after 72 hrs by Cell-titer Glo reagent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Children's Hospital of Philadelphia

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataIC50: 134nMAssay Description:Inhibition of CENP-E in human SK-N-FI cells assessed as decrease in cell viability after 72 hrs in presence of ERK1 siRNA by Cell-titer Glo reagent a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Children's Hospital of Philadelphia

Curated by ChEMBL
LigandPNGBDBM50652774(Gsk-923295a | Gsk923295 | GSK-295 | GSK-923295 | G...)
Affinity DataIC50: 283nMAssay Description:Inhibition of CENP-E in human SK-N-FI cells assessed as decrease in cell viability after 72 hrs by Cell-titer Glo reagent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed