Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50042095
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50:  150nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50:  180nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420298(CHEMBL2089033)
Affinity DataIC50:  270nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420298(CHEMBL2089033)
Affinity DataIC50:  370nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420299(CHEMBL2089034)
Affinity DataIC50:  390nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420299(CHEMBL2089034)
Affinity DataIC50:  450nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420298(CHEMBL2089033)
Affinity DataIC50:  600nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420299(CHEMBL2089034)
Affinity DataIC50:  610nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420300(CHEMBL2089035)
Affinity DataIC50:  660nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50:  710nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50420300(CHEMBL2089035)
Affinity DataIC50:  790nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420300(CHEMBL2089035)
Affinity DataIC50:  820nMAssay Description:Inhibition of human recombinant CDK5/p25 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50420298(CHEMBL2089033)
Affinity DataIC50:  890nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420300(CHEMBL2089035)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of human recombinant CDK9/cyclin T expressed in baculovirus-infected insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50420299(CHEMBL2089034)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of mouse recombinant CLK1 expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CK1 after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of mouse recombinant CLK1 expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50420297(CHEMBL2089032)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50420301(CHEMBL2089036)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of mouse recombinant CLK1 expressed in Escherichia coli after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed