Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50040343
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392945(CHEMBL2152245)
Affinity DataIC50: 110nMAssay Description:Inhibition of mouse COX2-mediated 2-arachidonoylglycerol oxygenation preincubated for 3 mins before 2-arachidonoylglycerol addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50295286(2-(3-benzoylphenyl)acetic acid | CHEMBL561718)
Affinity DataIC50: 500nMAssay Description:Inhibition of mouse COX2-mediated 2-arachidonoylglycerol oxygenation preincubated for 3 mins before 2-arachidonoylglycerol addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392945(CHEMBL2152245)
Affinity DataIC50: 600nMAssay Description:Inhibition of COX2-mediated 2-arachidonoylglycerol oxygenation in LPS/IFN-gamma-stimulated mouse RAW264.7 cells assessed as 2-AG to PGE2-G/PGD2-G con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50181914(2-(2-Fluoro-biphenyl-4-yl)-2-methyl-propionic acid...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of mouse COX2-mediated 2-arachidonoylglycerol oxygenation preincubated for 3 mins before 2-arachidonoylglycerol addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50172473((2R)-2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic ac...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of COX2-mediated 2-arachidonoylglycerol oxygenation in LPS/IFN-gamma-stimulated mouse RAW264.7 cells assessed as 2-AG to PGE2-G/PGD2-G con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM54706(2-(6-methoxynaphthalen-2-yl)ethanoic acid | 2-(6-m...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of mouse COX2-mediated 2-arachidonoylglycerol oxygenation preincubated for 3 mins before 2-arachidonoylglycerol addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392948(CHEMBL194760)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of mouse COX2-mediated 2-arachidonoylglycerol oxygenation preincubated for 3 mins before 2-arachidonoylglycerol addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392947(CHEMBL2152246)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse COX2-mediated 2-arachidonoylglycerol oxygenation preincubated for 3 mins before 2-arachidonoylglycerol addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392949(CHEMBL2152247)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of mouse COX2-mediated 2-arachidonoylglycerol oxygenation preincubated for 3 mins before 2-arachidonoylglycerol addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392951(CHEMBL2152352)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of mouse COX2-mediated 2-arachidonoylglycerol oxygenation preincubated for 3 mins before 2-arachidonoylglycerol addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392950(CHEMBL2152249)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mouse COX2-mediated 2-arachidonoylglycerol oxygenation preincubated for 3 mins before 2-arachidonoylglycerol addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50181914(2-(2-Fluoro-biphenyl-4-yl)-2-methyl-propionic acid...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of COX2-mediated 2-arachidonoylglycerol oxygenation in LPS/IFN-gamma-stimulated mouse RAW264.7 cells assessed as 2-AG to PGE2-G/PGD2-G con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50295285(Ibufenac | (4-Isobutyl-phenyl)-acetic acid | 2-(4-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of mouse COX2-mediated 2-arachidonoylglycerol oxygenation preincubated for 3 mins before 2-arachidonoylglycerol addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50060976((3-Phenoxy-phenyl)-acetic acid | CHEMBL107066)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of mouse COX2-mediated 2-arachidonoylglycerol oxygenation preincubated for 3 mins before 2-arachidonoylglycerol addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392946(CHEMBL205814)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of mouse COX2-mediated 2-arachidonoylglycerol oxygenation preincubated for 3 mins before 2-arachidonoylglycerol addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392948(CHEMBL194760)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of COX2-mediated 2-arachidonoylglycerol oxygenation in LPS/IFN-gamma-stimulated mouse RAW264.7 cells assessed as 2-AG to PGE2-G/PGD2-G con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed