Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50040263
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391678BDBM50391678(CHEMBL1569494)
Affinity DataIC50: 310nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391682BDBM50391682(CHEMBL2148167)
Affinity DataIC50: 330nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391691BDBM50391691(CHEMBL2148182)
Affinity DataIC50: 410nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391678BDBM50391678(CHEMBL1569494)
Affinity DataIC50: 420nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of IL1-beta production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391683BDBM50391683(CHEMBL2148176)
Affinity DataIC50: 420nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391690BDBM50391690(CHEMBL2148181)
Affinity DataIC50: 520nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391674BDBM50391674(CHEMBL2148171)
Affinity DataIC50: 710nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391687BDBM50391687(CHEMBL2148169)
Affinity DataIC50: 740nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391679BDBM50391679(CHEMBL2148166)
Affinity DataIC50: 820nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391686BDBM50391686(CHEMBL2148168)
Affinity DataIC50: 820nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391692BDBM50391692(CHEMBL2148170)
Affinity DataIC50: 820nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391693BDBM50391693(CHEMBL2148177)
Affinity DataIC50: 820nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391684BDBM50391684(CHEMBL2148183)
Affinity DataIC50: 930nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391676BDBM50391676(CHEMBL2148174)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391675BDBM50391675(CHEMBL2148173)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391673BDBM50391673(CHEMBL2148184)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391680BDBM50391680(CHEMBL2148172)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391678BDBM50391678(CHEMBL1569494)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of TNFalpha production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391694BDBM50391694(CHEMBL2148178)
Affinity DataIC50: 2.13E+3nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391688BDBM50391688(CHEMBL2148179)
Affinity DataIC50: 2.53E+3nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391681BDBM50391681(CHEMBL2148175)
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391689BDBM50391689(CHEMBL2148180)
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391695BDBM50391695(CHEMBL2148187)
Affinity DataIC50: 4.53E+3nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067040BDBM50067040(CHEMBL116438 | 1,7-bis(4-hydroxy-3-methoxyphenyl)1...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391677BDBM50391677(CHEMBL2148185)
Affinity DataIC50: 7.82E+4nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391685BDBM50391685(CHEMBL2148186)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed