Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50040626
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50226453(2-amino-6-[2-(3'-methoxy-1,1'-biphenyl-3-yl)ethyl]...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human BACE1 (43-454 amino acids) expressed in Escherichia coli BL21 using SEVNLDAEFRHDSGYEK-biotinafter 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397271(CHEMBL2169933)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human BACE1 (43-454 amino acids) expressed in Escherichia coli BL21 using SEVNLDAEFRHDSGYEK-biotinafter 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50226453(2-amino-6-[2-(3'-methoxy-1,1'-biphenyl-3-yl)ethyl]...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50226449(2-amino-6-[2-(1,1'-biphenyl-3-yl)ethyl]-3-methylpy...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of human BACE1 (43-454 amino acids) expressed in Escherichia coli BL21 using SEVNLDAEFRHDSGYEK-biotinafter 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397246(CHEMBL2172802)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397253(CHEMBL2172795)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397248(CHEMBL2172800)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397255(CHEMBL2172793)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397252(CHEMBL2172796)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397262(CHEMBL2169942)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397254(CHEMBL2172794)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397247(CHEMBL2172801)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397265(CHEMBL2169939)
Affinity DataIC50:  1.71E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397274(CHEMBL2169930)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibition of human BACE1 (43-454 amino acids) expressed in Escherichia coli BL21 using SEVNLDAEFRHDSGYEK-biotinafter 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397244(CHEMBL2172804)
Affinity DataIC50:  2.06E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397249(CHEMBL2172799)
Affinity DataIC50:  2.32E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397245(CHEMBL2172803)
Affinity DataIC50:  2.43E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397243(CHEMBL2169922)
Affinity DataIC50:  2.45E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397267(CHEMBL2169937)
Affinity DataIC50:  2.56E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50226449(2-amino-6-[2-(1,1'-biphenyl-3-yl)ethyl]-3-methylpy...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397250(CHEMBL2172798)
Affinity DataIC50:  3.41E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397266(CHEMBL2169938)
Affinity DataIC50:  3.94E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397261(CHEMBL2169943)
Affinity DataIC50:  4.65E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397258(CHEMBL2169946)
Affinity DataIC50:  5.07E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397257(CHEMBL2169947)
Affinity DataIC50:  5.33E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397251(CHEMBL2172797)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397260(CHEMBL2169944)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397241(CHEMBL2169924)
Affinity DataIC50:  5.99E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397242(CHEMBL2169923)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397268(CHEMBL2169936)
Affinity DataIC50:  1.03E+5nMAssay Description:Inhibition of human BACE1 (43-454 amino acids) expressed in Escherichia coli BL21 using SEVNLDAEFRHDSGYEK-biotinafter 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397256(CHEMBL2169916)
Affinity DataIC50:  1.16E+5nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397264(CHEMBL2169940)
Affinity DataIC50:  1.19E+5nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397279(CHEMBL2172792)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397278(CHEMBL2169926)
Affinity DataIC50:  1.57E+5nMAssay Description:Inhibition of human BACE1 (43-454 amino acids) expressed in Escherichia coli BL21 using SEVNLDAEFRHDSGYEK-biotinafter 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397259(CHEMBL2169945)
Affinity DataIC50:  1.65E+5nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50226446(2-amino-3-methyl-6-phenethyl-3H-pyrimidin-4-one | ...)
Affinity DataIC50:  1.71E+5nMAssay Description:Inhibition of human BACE1 (43-454 amino acids) expressed in Escherichia coli BL21 using SEVNLDAEFRHDSGYEK-biotinafter 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397263(CHEMBL2169941)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397240(CHEMBL2169925)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50226446(2-amino-3-methyl-6-phenethyl-3H-pyrimidin-4-one | ...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397273(CHEMBL2169931)
Affinity DataIC50:  5.02E+5nMAssay Description:Inhibition of human BACE1 (43-454 amino acids) expressed in Escherichia coli BL21 using SEVNLDAEFRHDSGYEK-biotinafter 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397272(CHEMBL2169932)
Affinity DataIC50:  6.14E+5nMAssay Description:Inhibition of human BACE1 (43-454 amino acids) expressed in Escherichia coli BL21 using SEVNLDAEFRHDSGYEK-biotinafter 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397277(CHEMBL2169927)
Affinity DataIC50:  6.19E+5nMAssay Description:Inhibition of human BACE1 (43-454 amino acids) expressed in Escherichia coli BL21 using SEVNLDAEFRHDSGYEK-biotinafter 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397270(CHEMBL2169934)
Affinity DataIC50:  1.11E+6nMAssay Description:Inhibition of human BACE1 (43-454 amino acids) expressed in Escherichia coli BL21 using SEVNLDAEFRHDSGYEK-biotinafter 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397269(CHEMBL2169935)
Affinity DataIC50:  1.85E+6nMAssay Description:Inhibition of human BACE1 (43-454 amino acids) expressed in Escherichia coli BL21 using SEVNLDAEFRHDSGYEK-biotinafter 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397276(CHEMBL2169928)
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of human BACE1 (43-454 amino acids) expressed in Escherichia coli BL21 using SEVNLDAEFRHDSGYEK-biotinafter 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50397275(CHEMBL2169929)
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of human BACE1 (43-454 amino acids) expressed in Escherichia coli BL21 using SEVNLDAEFRHDSGYEK-biotinafter 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50226439(2-amino-6-propylpyrimidin-4(3H)-one | CHEMBL235825)
Affinity DataIC50:  2.49E+6nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair