Compile Data Set for Download or QSAR
Report error Found 86 Enz. Inhib. hit(s) with all data for entry = 50040718
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398864BDBM50398864(CHEMBL2178164)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398863BDBM50398863(CHEMBL2178165)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACE1 in human KBV1 cells expressing APP 751 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnight...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398863BDBM50398863(CHEMBL2178165)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398882BDBM50398882(CHEMBL2178180)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398863BDBM50398863(CHEMBL2178165)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398868BDBM50398868(CHEMBL2178195)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398864BDBM50398864(CHEMBL2178164)
Affinity DataIC50: 8nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398864BDBM50398864(CHEMBL2178164)
Affinity DataIC50: 8nMAssay Description:Inhibition of BACE1 in human KBV1 cells expressing APP 751 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnight...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398883BDBM50398883(CHEMBL2178179)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398867BDBM50398867(CHEMBL2178161)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398866BDBM50398866(CHEMBL2178162)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398865BDBM50398865(CHEMBL2178163)
Affinity DataIC50: 10nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398870BDBM50398870(CHEMBL2178193)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398869BDBM50398869(CHEMBL2178194)
Affinity DataIC50: 20nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398869BDBM50398869(CHEMBL2178194)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398866BDBM50398866(CHEMBL2178162)
Affinity DataIC50: 20nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398881BDBM50398881(CHEMBL2178181)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398865BDBM50398865(CHEMBL2178163)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398874BDBM50398874(CHEMBL2178189)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398876BDBM50398876(CHEMBL2178187)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398877BDBM50398877(CHEMBL2178186)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398879BDBM50398879(CHEMBL2178184)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398884BDBM50398884(CHEMBL2178178)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398880BDBM50398880(CHEMBL2178183)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398875BDBM50398875(CHEMBL2178188)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398872BDBM50398872(CHEMBL2178191)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398871BDBM50398871(CHEMBL2178192)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398878BDBM50398878(CHEMBL2178185)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398873BDBM50398873(CHEMBL2178190)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398867BDBM50398867(CHEMBL2178161)
Affinity DataIC50: 70nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398870BDBM50398870(CHEMBL2178193)
Affinity DataIC50: 70nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398871BDBM50398871(CHEMBL2178192)
Affinity DataIC50: 90nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398888BDBM50398888(CHEMBL2178177)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398868BDBM50398868(CHEMBL2178195)
Affinity DataIC50: 140nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398893BDBM50398893(CHEMBL2178172)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398891BDBM50398891(CHEMBL2178174)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398863BDBM50398863(CHEMBL2178165)
Affinity DataIC50: 180nMAssay Description:Inhibition of BACE1 in human KBV1 cells expressing APP 751 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnight...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398864BDBM50398864(CHEMBL2178164)
Affinity DataIC50: 180nMAssay Description:Inhibition of BACE1 in human KBV1 cells expressing APP 751 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnight...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398902BDBM50398902(CHEMBL2178202)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398872BDBM50398872(CHEMBL2178191)
Affinity DataIC50: 210nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398881BDBM50398881(CHEMBL2178181)
Affinity DataIC50: 240nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398898BDBM50398898(CHEMBL2178167)
Affinity DataKi:  270nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398897BDBM50398897(CHEMBL2178168)
Affinity DataKi:  280nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398887BDBM50398887(CHEMBL2178182)
Affinity DataKi:  280nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398885BDBM50398885(CHEMBL2178204)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398882BDBM50398882(CHEMBL2178180)
Affinity DataIC50: 310nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398882BDBM50398882(CHEMBL2178180)
Affinity DataIC50: 310nMAssay Description:Inhibition of BACE1 in human KBV1 cells expressing APP 751 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnight...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398874BDBM50398874(CHEMBL2178189)
Affinity DataIC50: 330nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398894BDBM50398894(CHEMBL2178171)
Affinity DataKi:  430nMAssay Description:Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398879BDBM50398879(CHEMBL2178184)
Affinity DataIC50: 430nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing APP 695 Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production after overnig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
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