Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50040732
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399081BDBM50399081(CHEMBL2179326)
Affinity DataEC50:  10nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399088BDBM50399088(CHEMBL2179319)
Affinity DataIC50: 15nMAssay Description:Binding affinity to human mGlu2R expressed in CHO cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399088BDBM50399088(CHEMBL2179319)
Affinity DataEC50:  17nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399086BDBM50399086(CHEMBL2179321)
Affinity DataEC50:  24nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399085BDBM50399085(CHEMBL2179322)
Affinity DataEC50:  39nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399094BDBM50399094(CHEMBL2179313)
Affinity DataEC50:  55nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399099BDBM50399099(CHEMBL2179333)
Affinity DataEC50:  56nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399098BDBM50399098(CHEMBL2179309)
Affinity DataEC50:  74nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399093BDBM50399093(CHEMBL2179314)
Affinity DataEC50:  102nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399087BDBM50399087(CHEMBL2179320)
Affinity DataEC50:  116nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399091BDBM50399091(CHEMBL2179316)
Affinity DataEC50:  116nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399100BDBM50399100(CHEMBL2179332)
Affinity DataEC50:  125nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399084BDBM50399084(CHEMBL2179323)
Affinity DataEC50:  149nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399102BDBM50399102(CHEMBL2179330)
Affinity DataEC50:  155nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399090BDBM50399090(CHEMBL2179317)
Affinity DataEC50:  178nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399088BDBM50399088(CHEMBL2179319)
Affinity DataEC50:  270nMAssay Description:Agonist activity at human mGlu2R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399101BDBM50399101(CHEMBL2179331)
Affinity DataEC50:  299nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399092BDBM50399092(CHEMBL2179315)
Affinity DataEC50:  386nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399083BDBM50399083(CHEMBL2179324)
Affinity DataEC50:  400nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399096BDBM50399096(CHEMBL2179311)
Affinity DataEC50:  468nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399104BDBM50399104(CHEMBL2179328)
Affinity DataEC50:  501nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399080BDBM50399080(CHEMBL2179327)
Affinity DataEC50:  519nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399103BDBM50399103(CHEMBL2179329)
Affinity DataEC50:  696nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399089BDBM50399089(CHEMBL2179318)
Affinity DataEC50:  944nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399095BDBM50399095(CHEMBL2179312)
Affinity DataEC50:  1.12E+3nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399082BDBM50399082(CHEMBL2179325)
Affinity DataEC50:  1.23E+3nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399097BDBM50399097(CHEMBL2179310)
Affinity DataEC50:  1.23E+3nMAssay Description:Positive allosteric modulator activity at human mGlu2R expressed in CHO cells incubated for 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399088BDBM50399088(CHEMBL2179319)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399088BDBM50399088(CHEMBL2179319)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399088BDBM50399088(CHEMBL2179319)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399088BDBM50399088(CHEMBL2179319)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Janssen-Cilag

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399088BDBM50399088(CHEMBL2179319)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed