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Found 22 Enz. Inhib. hit(s) with all data for entry = 50040931
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402339(CHEMBL2206666)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of human VEGFR2 for 5 mins prior to addition of 10 uM ATP using poly-GluTyr by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402339(CHEMBL2206666)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of VEGFR1 by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402345(CHEMBL2206663)
Affinity DataIC50:  12nMAssay Description:Inhibition of human VEGFR2 for 5 mins prior to addition of 10 uM ATP using poly-GluTyr by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402339(CHEMBL2206666)
Affinity DataIC50:  13nMAssay Description:Inhibition of PDGFRalpha by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402339(CHEMBL2206666)
Affinity DataIC50:  15nMAssay Description:Inhibition of PDGFRbeta by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402340(CHEMBL2206668)
Affinity DataIC50:  18nMAssay Description:Inhibition of human VEGFR2 for 5 mins prior to addition of 10 uM ATP using poly-GluTyr by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402344(CHEMBL2203321)
Affinity DataIC50:  29nMAssay Description:Inhibition of human VEGFR2 for 5 mins prior to addition of 10 uM ATP using poly-GluTyr by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402346(CHEMBL2206662)
Affinity DataIC50:  52nMAssay Description:Inhibition of human VEGFR2 for 5 mins prior to addition of 10 uM ATP using poly-GluTyr by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402342(CHEMBL2206665)
Affinity DataIC50:  80nMAssay Description:Inhibition of human VEGFR2 for 5 mins prior to addition of 10 uM ATP using poly-GluTyr by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402339(CHEMBL2206666)
Affinity DataIC50:  120nMAssay Description:Inhibition of c-Kit by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402339(CHEMBL2206666)
Affinity DataIC50:  290nMAssay Description:Inhibition of B-raf using [gamma-33P]ATP by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402341(CHEMBL2206667)
Affinity DataIC50:  640nMAssay Description:Inhibition of human VEGFR2 for 5 mins prior to addition of 10 uM ATP using poly-GluTyr by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402339(CHEMBL2206666)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of FGFR3 by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402339(CHEMBL2206666)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of Tie-2 by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402339(CHEMBL2206666)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of FGFR1 by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402347(CHEMBL2206661)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of human VEGFR2 for 5 mins prior to addition of 10 uM ATP using poly-GluTyr by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402339(CHEMBL2206666)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of insulin receptor by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402339(CHEMBL2206666)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IGF1-R by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402339(CHEMBL2206666)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GSK3beta using [gamma-33P]ATP by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402339(CHEMBL2206666)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR4 using FGFR4 and ATP by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402339(CHEMBL2206666)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of c-Met by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50402343(CHEMBL2206664)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human VEGFR2 for 5 mins prior to addition of 10 uM ATP using poly-GluTyr by AlphaScreen analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed