Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50040328
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50099491(cid_3392731 | CHEMBL21241 | 2-(4-{2-[3-Cyclohexyl-...)
Affinity DataEC50:  200nMAssay Description:Transactivation of PPARalpha expressed in HEK293A cells co-expressing GAL4 after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50392674(CHEMBL2153834)
Affinity DataIC50: 480nMAssay Description:Binding affinity to PPARalpha LBD after 2 hrs by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50392675(CHEMBL2153835)
Affinity DataIC50: 600nMAssay Description:Antagonist activity at PPARalpha expressed in HEK293 cells co-expressing GAL4 assessed as inhibition of GW7647-induced transactivation activity after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50392677(CHEMBL2153837)
Affinity DataIC50: 600nMAssay Description:Binding affinity to PPARalpha LBD after 2 hrs by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50392677(CHEMBL2153837)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at PPARalpha expressed in HEK293 cells co-expressing GAL4 assessed as inhibition of GW7647-induced transactivation activity after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50392675(CHEMBL2153835)
Affinity DataIC50: 890nMAssay Description:Binding affinity to PPARalpha LBD after 2 hrs by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50392679(CHEMBL2153839)
Affinity DataIC50: 900nMAssay Description:Antagonist activity at PPARalpha expressed in HEK293 cells co-expressing GAL4 assessed as inhibition of GW7647-induced transactivation activity after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50392679(CHEMBL2153839)
Affinity DataIC50: 950nMAssay Description:Binding affinity to PPARalpha LBD after 2 hrs by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50392671(CHEMBL2153833)
Affinity DataEC50:  1.59E+3nMAssay Description:Transactivation of PPARalpha expressed in HEK293A cells co-expressing GAL4 after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50392678(CHEMBL2153838)
Affinity DataIC50: 5.10E+3nMAssay Description:Antagonist activity at PPARalpha expressed in HEK293 cells co-expressing GAL4 assessed as inhibition of GW7647-induced transactivation activity after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50392673(CHEMBL2153843)
Affinity DataEC50:  7.10E+3nMAssay Description:Transactivation of PPARalpha expressed in HEK293A cells co-expressing GAL4 after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50392674(CHEMBL2153834)
Affinity DataIC50: 8.87E+3nMAssay Description:Antagonist activity at PPARalpha expressed in HEK293 cells co-expressing GAL4 assessed as inhibition of GW7647-induced transactivation activity after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50392672(CHEMBL2153840)
Affinity DataEC50:  1.07E+4nMAssay Description:Transactivation of PPARalpha expressed in HEK293A cells co-expressing GAL4 after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50392676(CHEMBL2153836)
Affinity DataIC50: 4.65E+4nMAssay Description:Antagonist activity at PPARalpha expressed in HEK293 cells co-expressing GAL4 assessed as inhibition of GW7647-induced transactivation activity after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM28699(2-(4-chlorophenoxy)-2-methylpropanoic acid | CHEMB...)
Affinity DataEC50:  5.50E+4nMAssay Description:Transactivation of PPARalpha expressed in HEK293A cells co-expressing GAL4 after 16 to 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
D'Annunzio University of Chieti

Curated by ChEMBL
LigandPNGBDBM50392680(CHEMBL2153842)
Affinity DataIC50: 6.85E+4nMAssay Description:Antagonist activity at PPARalpha expressed in HEK293 cells co-expressing GAL4 assessed as inhibition of GW7647-induced transactivation activity after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed