Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50042662
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50428976(CHEMBL2333219)
Affinity DataIC50: 0.277nMAssay Description:Inhibition of PDE5 (unknown origin) using FAM-cGMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50428975(CHEMBL2333220)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PDE5 (unknown origin) using FAM-cGMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50428971(CHEMBL2333224)
Affinity DataIC50: 0.630nMAssay Description:Inhibition of PDE5 (unknown origin) using FAM-cGMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM14776(CHEMBL1520 | 2-{2-ethoxy-5-[(4-ethylpiperazine-1-)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PDE5 (unknown origin) using FAM-cGMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PDE5 (unknown origin) using FAM-cGMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of PDE5 (unknown origin) using FAM-cGMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50428972(CHEMBL2333223)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of PDE5 (unknown origin) using FAM-cGMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50428974(CHEMBL2333221)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of PDE5 (unknown origin) using FAM-cGMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50428973(CHEMBL2333222)
Affinity DataIC50: 15nMAssay Description:Inhibition of PDE5 (unknown origin) using FAM-cGMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM14776(CHEMBL1520 | 2-{2-ethoxy-5-[(4-ethylpiperazine-1-)...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of PDE2 (unknown origin) using FAM-cGMP and FAM-cAMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE2 (unknown origin) using FAM-cGMP and FAM-cAMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50428975(CHEMBL2333220)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE2 (unknown origin) using FAM-cGMP and FAM-cAMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50428976(CHEMBL2333219)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE2 (unknown origin) using FAM-cGMP and FAM-cAMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE2 (unknown origin) using FAM-cGMP and FAM-cAMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed