Compile Data Set for Download or QSAR
maximum 50k data
Found 49 Enz. Inhib. hit(s) with all data for entry = 50043049
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435091(CHEMBL2391524)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435086(CHEMBL2391528)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435096(CHEMBL2391519)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435090(CHEMBL2391525)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435095(CHEMBL2391520)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435098(CHEMBL2391516)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435094(CHEMBL2391521)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435087(CHEMBL2390962)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435080(CHEMBL2391518)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor in presence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435080(CHEMBL2391518)
Affinity DataIC50:  14nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50434979(CHEMBL2385906)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor in presence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435102(CHEMBL2391512)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50434979(CHEMBL2385906)
Affinity DataIC50:  17nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435101(CHEMBL2391513)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435100(CHEMBL2391514)
Affinity DataIC50:  30nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435099(CHEMBL2391515)
Affinity DataIC50:  30nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435093(CHEMBL2391522)
Affinity DataIC50:  45nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435088(CHEMBL2391527)
Affinity DataIC50:  50nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435080(CHEMBL2391518)
Affinity DataIC50:  54nMAssay Description:Antagonist activity at PGD2-induced human CRTh2 receptor activation expressed in HEK293 cells assessed as intracellular Ca2+ liberation by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435097(CHEMBL2391517)
Affinity DataIC50:  60nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435092(CHEMBL2391523)
Affinity DataIC50:  100nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50434979(CHEMBL2385906)
Affinity DataIC50:  110nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435084(CHEMBL2391530)
Affinity DataIC50:  140nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435082(CHEMBL2391532)
Affinity DataIC50:  145nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435080(CHEMBL2391518)
Affinity DataIC50:  160nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50434979(CHEMBL2385906)
Affinity DataIC50:  170nMAssay Description:Antagonist activity at PGD2-induced human CRTh2 receptor activation expressed in HEK293 cells assessed as intracellular Ca2+ liberation by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435112(CHEMBL2391534)
Affinity DataIC50:  200nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435111(CHEMBL2391536)
Affinity DataIC50:  210nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435089(CHEMBL2391526)
Affinity DataIC50:  290nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435081(CHEMBL2391533)
Affinity DataIC50:  430nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435108(CHEMBL2391506)
Affinity DataIC50:  430nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435083(CHEMBL2391531)
Affinity DataIC50:  490nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435109(CHEMBL2391505)
Affinity DataIC50:  500nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435105(CHEMBL2391509)
Affinity DataIC50:  510nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435104(CHEMBL2391510)
Affinity DataIC50:  560nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435109(CHEMBL2391505)
Affinity DataIC50:  600nMAssay Description:Antagonist activity at PGD2-induced human CRTh2 receptor activation expressed in HEK293 cells assessed as intracellular Ca2+ liberation by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435085(CHEMBL2391529)
Affinity DataIC50:  690nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435110(CHEMBL2391535)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435106(CHEMBL2391508)
Affinity DataIC50:  2.60E+3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435103(CHEMBL2391511)
Affinity DataIC50:  4.40E+3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435107(CHEMBL2391507)
Affinity DataIC50:  5.90E+3nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435080(CHEMBL2391518)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of PGD2 binding to human DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435080(CHEMBL2391518)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435080(CHEMBL2391518)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50434979(CHEMBL2385906)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PGD2 binding to human DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50434979(CHEMBL2385906)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50434979(CHEMBL2385906)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonist activity at human TP2 receptor assessed as inhibition of U46619-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50435080(CHEMBL2391518)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonist activity at human TP2 receptor assessed as inhibition of U46619-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50434979(CHEMBL2385906)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed