Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50042667
TargetMetabotropic glutamate receptor 5(Human)
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50231755(6,6-dimethyl-2-phenylethynyl-7,8-dihydro-6H-quinol...)
Affinity DataIC50: 20nMAssay Description:Modulation of mGluR5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429062(CHEMBL2335279)
Affinity DataIC50: 410nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FDSS6000 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429061(CHEMBL2335285)
Affinity DataIC50: 430nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FDSS6000 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429059(CHEMBL2335295)
Affinity DataIC50: 750nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FDSS6000 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429060(CHEMBL2335291)
Affinity DataIC50: 940nMAssay Description:Antagonist activity at human mGluR5 expressed in HEK293 cells assessed as inhibition of L-glutamate-induced calcium mobilization by FDSS6000 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429060(CHEMBL2335291)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429059(CHEMBL2335295)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429062(CHEMBL2335279)
Affinity DataIC50: 6.17E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50429061(CHEMBL2335285)
Affinity DataIC50: 6.53E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed