TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 2.10E+3nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 2.10E+3nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 2.20E+3nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 8.50E+3nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Antagonist activity at rat muscarinic M1 receptor isolated from brainMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 372nMAssay Description:Antagonist activity at rat muscarinic M2 receptor isolated from brainMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Non-competitive antagonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of nicotine-induced calcium influx incub...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Non-competitive antagonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of nicotine-induced calcium influx incub...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Non-competitive antagonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of nicotine-induced calcium influx incub...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Non-competitive antagonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of nicotine-induced calcium influx incub...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Non-competitive antagonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of nicotine-induced calcium influx incub...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataIC50: 603nMAssay Description:Non-competitive antagonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of nicotine-induced calcium influx incub...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Agonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataEC50: 9.00E+3nMAssay Description:Agonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair