Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50042523
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427155BDBM50427155(CHEMBL2323770)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427138BDBM50427138(CHEMBL2323775 | MK-8033)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427143BDBM50427143(CHEMBL2323783)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427172BDBM50427172(CHEMBL2323777)
Affinity DataIC50: 2nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50347659BDBM50347659(CHEMBL1802916 | MK-2461 | US20250129067, Compound ...)
Affinity DataIC50: 2nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50347658BDBM50347658(CHEMBL1802917)
Affinity DataIC50: 3nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427153BDBM50427153(CHEMBL2323772)
Affinity DataIC50: 3nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427154BDBM50427154(CHEMBL2323771)
Affinity DataIC50: 3nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427151BDBM50427151(CHEMBL2323774)
Affinity DataIC50: 3nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427138BDBM50427138(CHEMBL2323775 | MK-8033)
Affinity DataKd:  3.20nMAssay Description:Binding affinity to phosphorylated c-MET kinase domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50347681BDBM50347681(CHEMBL1802829)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427156BDBM50427156(CHEMBL2323769)
Affinity DataIC50: 5nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427157BDBM50427157(CHEMBL2324128)
Affinity DataIC50: 6nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50427138BDBM50427138(CHEMBL2323775 | MK-8033)
Affinity DataIC50: 7nMAssay Description:Inhibition of RON (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50347681BDBM50347681(CHEMBL1802829)
Affinity DataIC50: 7nMAssay Description:Inhibition of RON (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427144BDBM50427144(CHEMBL2323782)
Affinity DataIC50: 8nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427152BDBM50427152(CHEMBL2323773)
Affinity DataIC50: 8nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427138BDBM50427138(CHEMBL2323775 | MK-8033)
Affinity DataKd:  10nMAssay Description:Binding affinity to unphosphorylated c-MET kinase domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427145BDBM50427145(CHEMBL2323781)
Affinity DataIC50: 10nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427159BDBM50427159(CHEMBL2324126)
Affinity DataIC50: 11nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427161BDBM50427161(CHEMBL2324124)
Affinity DataIC50: 14nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427138BDBM50427138(CHEMBL2323775 | MK-8033)
Affinity DataIC50: 29nMAssay Description:Inhibition of HGF-stimulated c-MET (unknown origin) autophosphorylation at tyrosine 1349 expressed in human GTL16 cells after 2 hrs by Western blotti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427139BDBM50427139(CHEMBL2324117)
Affinity DataIC50: 32nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427160BDBM50427160(CHEMBL2324125)
Affinity DataIC50: 33nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427164BDBM50427164(CHEMBL2324121)
Affinity DataIC50: 42nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427163BDBM50427163(CHEMBL2324122)
Affinity DataIC50: 45nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427158BDBM50427158(CHEMBL2324127)
Affinity DataIC50: 52nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427162BDBM50427162(CHEMBL2324123)
Affinity DataIC50: 53nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427170BDBM50427170(CHEMBL2323779)
Affinity DataIC50: 55nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427142BDBM50427142(CHEMBL2324129)
Affinity DataIC50: 60nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427171BDBM50427171(CHEMBL2323778)
Affinity DataIC50: 67nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427140BDBM50427140(CHEMBL2324116)
Affinity DataIC50: 70nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50347681BDBM50347681(CHEMBL1802829)
Affinity DataIC50: 80nMAssay Description:Inhibition of HGF-stimulated c-MET (unknown origin) autophosphorylation at tyrosine 1349 expressed in human GTL16 cells after 2 hrs by Western blotti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50347657BDBM50347657(CHEMBL1615181)
Affinity DataIC50: 85nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427141BDBM50427141(CHEMBL2324113)
Affinity DataIC50: 94nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427167BDBM50427167(CHEMBL2324118)
Affinity DataIC50: 98nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427166BDBM50427166(CHEMBL2324119)
Affinity DataIC50: 163nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427146BDBM50427146(CHEMBL2323780)
Affinity DataIC50: 190nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50427139BDBM50427139(CHEMBL2324117)
Affinity DataIC50: 403nMAssay Description:Inhibition of RON (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427138BDBM50427138(CHEMBL2323775 | MK-8033)
Affinity DataIC50: 582nMAssay Description:Inhibition of c-MET (unknown origin) expressed in human GTL16 cells assessed as inhibition of cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50427142BDBM50427142(CHEMBL2324129)
Affinity DataIC50: 861nMAssay Description:Inhibition of RON (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50427140BDBM50427140(CHEMBL2324116)
Affinity DataIC50: 912nMAssay Description:Inhibition of RON (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427148BDBM50427148(CHEMBL2323784)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427168BDBM50427168(CHEMBL2324115)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427149BDBM50427149(CHEMBL2324130)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50427141BDBM50427141(CHEMBL2324113)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of RON (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427165BDBM50427165(CHEMBL2324120)
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50347681BDBM50347681(CHEMBL1802829)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of c-MET (unknown origin) expressed in human GTL16 cells assessed as inhibition of cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427169BDBM50427169(CHEMBL2324114)
Affinity DataIC50: 3.19E+3nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427147BDBM50427147(CHEMBL2324112)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
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