Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50042714
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human SERT expressed in HEK293-MSR cells by 5-HT uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 560nMAssay Description:Inhibition of human SERT expressed in HEK293-MSR cells by 5-HT uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50429853(CHEMBL2332389)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human SERT expressed in HEK293-MSR cells by 5-HT uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50429852(CHEMBL2332390)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human SERT expressed in HEK293-MSR cells by 5-HT uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50429854(CHEMBL2332388)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human SERT expressed in HEK293-MSR cells by 5-HT uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50429851(CHEMBL2332391)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of human SERT expressed in HEK293-MSR cells by 5-HT uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed