Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50042543
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50: 300nMAssay Description:Inhibition of renin in human plasma using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate addition measured after 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5-HT2A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5-HT1A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 5-HT2B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427568(CHEMBL2322608)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427567(CHEMBL2322609)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427566(CHEMBL2322894)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427571(CHEMBL2322605)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427565(CHEMBL2322896)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427569(CHEMBL2322607)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427570(CHEMBL2322606)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427565(CHEMBL2322896)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant cathepsin-D expressed in baculovirus-infected insect sf9 cells using Ac- E-D(EDANS)-KPILFFRLG-K(Dabcyl)-E-Amid as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCathepsin E(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427565(CHEMBL2322896)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant cathepsin-E expressed in Escherichia coli using Ac- E-D(EDANS)-KPILFFRLG-K(Dabcyl)-E-Amid as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427565(CHEMBL2322896)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of human ERG by dofetilide binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427572(CHEMBL2322897)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human recombinant renin expressed in CHO cells using RE(EDANS)IHPFHLVIHTK(Dabcyl)R as substrate incubated for 1 hr prior to substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGastricsin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427565(CHEMBL2322896)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human recombinant pepsin C expressed in Escherichia coli using Dabcyl-E-R-Nle-F-L-S-F-P-EDANS as substrate incubated for 1 hr prior to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCathepsin D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant cathepsin-D expressed in baculovirus-infected insect sf9 cells using Ac- E-D(EDANS)-KPILFFRLG-K(Dabcyl)-E-Amid as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCathepsin E(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant cathepsin-E expressed in Escherichia coli using Ac- E-D(EDANS)-KPILFFRLG-K(Dabcyl)-E-Amid as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant BACE-1 expressed in baculovirus-infected insect sf9 cells using RE( EDANS)-EVNLDAEF-K(DABSYL)-R as substrate incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGastricsin(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant pepsin C expressed in Escherichia coli using Dabcyl-E-R-Nle-F-L-S-F-P-EDANS as substrate incubated for 1 hr prior to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50427564(CHEMBL2322611)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant BACE-2 expressed in baculovirus-infected insect sf9 cells using RE( EDANS)-EVNLDAEF-K(DABSYL)-R as substrate incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed