Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50042902
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432976BDBM50432976(CHEMBL2377740)
Affinity DataEC50:  20nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432950BDBM50432950(CHEMBL2377735)
Affinity DataEC50:  20nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432968BDBM50432968(CHEMBL2377748)
Affinity DataEC50:  30nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432967BDBM50432967(CHEMBL2377749)
Affinity DataEC50:  30nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432973BDBM50432973(CHEMBL2377743)
Affinity DataEC50:  30nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432975BDBM50432975(CHEMBL2377741)
Affinity DataEC50:  30nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432972BDBM50432972(CHEMBL2377744)
Affinity DataEC50:  40nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432970BDBM50432970(CHEMBL2377746)
Affinity DataEC50:  60nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432949BDBM50432949(CHEMBL2377736)
Affinity DataEC50:  60nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432969BDBM50432969(CHEMBL2377747)
Affinity DataEC50:  80nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432958BDBM50432958(CHEMBL2377727)
Affinity DataEC50:  80nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432977BDBM50432977(CHEMBL2377739)
Affinity DataEC50:  80nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432960BDBM50432960(Tecalcet HCl | NPS-R-568 | KRN-568 | R-568 | Norca...)
Affinity DataEC50:  80nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432963BDBM50432963(CHEMBL2377752)
Affinity DataEC50:  80nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432971BDBM50432971(CHEMBL2377745)
Affinity DataEC50:  90nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432966BDBM50432966(CHEMBL2375383)
Affinity DataEC50:  100nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432948BDBM50432948(CHEMBL2377737)
Affinity DataEC50:  150nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432953BDBM50432953(CHEMBL2377732)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432955BDBM50432955(CHEMBL2377730)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432961BDBM50432961(CHEMBL2375386)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432965BDBM50432965(CHEMBL2377750)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432964BDBM50432964(CHEMBL2377751)
Affinity DataEC50:  200nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432954BDBM50432954(CHEMBL2377731)
Affinity DataEC50:  300nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432978BDBM50432978(CHEMBL2377738)
Affinity DataEC50:  300nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432951BDBM50432951(CHEMBL2377734)
Affinity DataEC50:  400nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432956BDBM50432956(CHEMBL2377729)
Affinity DataEC50:  400nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432957BDBM50432957(CHEMBL2377728)
Affinity DataEC50:  450nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432974BDBM50432974(CHEMBL2377742)
Affinity DataEC50:  600nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432962BDBM50432962(CHEMBL2375385)
Affinity DataEC50:  1.00E+3nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432959BDBM50432959(CHEMBL2377726)
Affinity DataEC50:  1.00E+3nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Galapagos

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432952BDBM50432952(CHEMBL2377733)
Affinity DataEC50:  1.70E+3nMAssay Description:Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed