Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50042793
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50310190(2-p-Tolyl-chromen-4-one | 2-p-tolyl-4H-chromen-4-o...)
Affinity DataIC50: 52nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50028962(flavone | CHEMBL275638)
Affinity DataIC50: 140nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50157555(2-(3,4-dihydroxyphenyl)-4H-chromen-4-one | 3',4'-d...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50157555(2-(3,4-dihydroxyphenyl)-4H-chromen-4-one | 3',4'-d...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | cid_261391 | 2...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM26659(7-hydroxy-2-(3-hydroxyphenyl)-4H-chromen-4-one | 7...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50431165(NSC-22356 | CHEMBL147552 | 2-(3-hydroxyphenyl)-4H-...)
Affinity DataIC50: 310nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50431165(NSC-22356 | CHEMBL147552 | 2-(3-hydroxyphenyl)-4H-...)
Affinity DataIC50: 310nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50028962(flavone | CHEMBL275638)
Affinity DataIC50: 320nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM85573(7-Hydroxy-flavone, 5h)
Affinity DataIC50: 450nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM85573(7-Hydroxy-flavone, 5h)
Affinity DataIC50: 560nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM26659(7-hydroxy-2-(3-hydroxyphenyl)-4H-chromen-4-one | 7...)
Affinity DataIC50: 620nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50077325(7,3',4'-Trihydroxyflavone | 2-(3,4-dihydroxyphenyl...)
Affinity DataIC50: 630nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50077325(7,3',4'-Trihydroxyflavone | 2-(3,4-dihydroxyphenyl...)
Affinity DataIC50: 870nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | cid_261391 | 2...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50310190(2-p-Tolyl-chromen-4-one | 2-p-tolyl-4H-chromen-4-o...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50157555(2-(3,4-dihydroxyphenyl)-4H-chromen-4-one | 3',4'-d...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50028962(flavone | CHEMBL275638)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50431165(NSC-22356 | CHEMBL147552 | 2-(3-hydroxyphenyl)-4H-...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50077325(7,3',4'-Trihydroxyflavone | 2-(3,4-dihydroxyphenyl...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM26659(7-hydroxy-2-(3-hydroxyphenyl)-4H-chromen-4-one | 7...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM89825(2-(4-Fluoro-phenyl)-chromen-4-one | cid_261391 | 2...)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50310190(2-p-Tolyl-chromen-4-one | 2-p-tolyl-4H-chromen-4-o...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM85573(7-Hydroxy-flavone, 5h)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed