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Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 50006083
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496801(CHEMBL3222273)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496803(CHEMBL3218037)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496811(CHEMBL3222274)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496800(CHEMBL3218036)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496802(CHEMBL3218039)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496812(CHEMBL3222276)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496825(CHEMBL3218041)
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496809(CHEMBL3218040)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496810(CHEMBL3218038)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496805(CHEMBL3222275)
Affinity DataIC50: 81nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496818(CHEMBL3222277)
Affinity DataIC50: 95nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496820(CHEMBL3218042)
Affinity DataIC50: 168nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496817(CHEMBL3222278)
Affinity DataIC50: 199nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496826(CHEMBL3218044)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496824(CHEMBL3218043)
Affinity DataIC50: 415nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496816(CHEMBL3218029)
Affinity DataIC50: 610nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496808(CHEMBL3218045)
Affinity DataIC50: 635nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496804(CHEMBL3218030)
Affinity DataIC50: 635nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496821(CHEMBL3218032)
Affinity DataIC50: 645nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496812(CHEMBL3222276)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant PDE3A assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496803(CHEMBL3218037)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of human recombinant PDE4B assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496822(CHEMBL3222279)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496802(CHEMBL3218039)
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of human recombinant PDE4B assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496803(CHEMBL3218037)
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of human recombinant PDE4A assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496812(CHEMBL3222276)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant PDE3B assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496815(CHEMBL3218031)
Affinity DataIC50: 3.05E+3nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496802(CHEMBL3218039)
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of human recombinant PDE4A assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496800(CHEMBL3218036)
Affinity DataIC50: 3.43E+3nMAssay Description:Inhibition of human recombinant PDE4B assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496803(CHEMBL3218037)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of human recombinant PDE3B assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496800(CHEMBL3218036)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of human recombinant PDE4A assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496811(CHEMBL3222274)
Affinity DataIC50: 4.18E+3nMAssay Description:Inhibition of human recombinant PDE4A assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496814(CHEMBL3218033)
Affinity DataIC50: 4.25E+3nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496813(CHEMBL3218035)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496811(CHEMBL3222274)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human recombinant PDE3B assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496811(CHEMBL3222274)
Affinity DataIC50: 5.06E+3nMAssay Description:Inhibition of human recombinant PDE4B assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496806(CHEMBL3218034)
Affinity DataIC50: 5.15E+3nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496812(CHEMBL3222276)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant PDE4A assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496812(CHEMBL3222276)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human recombinant PDE4B assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496827(CHEMBL3222271)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496823(CHEMBL3222270)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496802(CHEMBL3218039)
Affinity DataIC50: 9.75E+3nMAssay Description:Inhibition of human recombinant PDE3B assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496819(CHEMBL3222272)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496807(CHEMBL3222269)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human recombinant PDE10A catalytic domain assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496801(CHEMBL3222273)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of human recombinant PDE3B assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496801(CHEMBL3222273)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of human recombinant PDE3A assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496803(CHEMBL3218037)
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of human recombinant PDE3A assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496811(CHEMBL3222274)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human recombinant PDE3A assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496801(CHEMBL3222273)
Affinity DataIC50: 3.15E+4nMAssay Description:Inhibition of human recombinant PDE4B assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496802(CHEMBL3218039)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of human recombinant PDE3A assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50496800(CHEMBL3218036)
Affinity DataIC50: 8.27E+4nMAssay Description:Inhibition of human recombinant PDE3B assessed reduction in [3H]cAMP hydrolysis preincubated with enzyme for 5 mins prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
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