Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50005355
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491458BDBM50491458(CHEMBL2381774)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491458BDBM50491458(CHEMBL2381774)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491465BDBM50491465(CHEMBL2381773)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491465BDBM50491465(CHEMBL2381773)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491462BDBM50491462(CHEMBL2381761)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491462BDBM50491462(CHEMBL2381761)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21190BDBM21190(CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...)
Affinity DataIC50: 42nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21190BDBM21190(CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...)
Affinity DataIC50: 42nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491457BDBM50491457(CHEMBL2381770)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491457BDBM50491457(CHEMBL2381770)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491459BDBM50491459(CHEMBL2381760)
Affinity DataIC50: 182nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491459BDBM50491459(CHEMBL2381760)
Affinity DataIC50: 182nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491456BDBM50491456(CHEMBL2381757)
Affinity DataIC50: 182nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491456BDBM50491456(CHEMBL2381757)
Affinity DataIC50: 182nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491448BDBM50491448(CHEMBL2381762)
Affinity DataIC50: 2.63E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491448BDBM50491448(CHEMBL2381762)
Affinity DataIC50: 2.63E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491455BDBM50491455(CHEMBL2381767)
Affinity DataIC50: 4.37E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491455BDBM50491455(CHEMBL2381767)
Affinity DataIC50: 4.37E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176050BDBM50176050(8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-pu...)
Affinity DataIC50: 5.25E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176050BDBM50176050(8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-pu...)
Affinity DataIC50: 5.25E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491454BDBM50491454(CHEMBL2381758)
Affinity DataIC50: 9.12E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491454BDBM50491454(CHEMBL2381758)
Affinity DataIC50: 9.12E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491449BDBM50491449(CHEMBL2381763)
Affinity DataIC50: 9.77E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491464BDBM50491464(CHEMBL2381759)
Affinity DataIC50: 9.77E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491464BDBM50491464(CHEMBL2381759)
Affinity DataIC50: 9.77E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491449BDBM50491449(CHEMBL2381763)
Affinity DataIC50: 9.77E+3nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491452BDBM50491452(CHEMBL2381771)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491463BDBM50491463(CHEMBL2381768)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491460BDBM50491460(CHEMBL2381766)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491461BDBM50491461(CHEMBL2381764)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491463BDBM50491463(CHEMBL2381768)
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491460BDBM50491460(CHEMBL2381766)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491452BDBM50491452(CHEMBL2381771)
Affinity DataIC50: 2.57E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491461BDBM50491461(CHEMBL2381764)
Affinity DataIC50: 5.50E+4nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491451BDBM50491451(CHEMBL2381769)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491450BDBM50491450(CHEMBL2381772)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491453BDBM50491453(CHEMBL2381765)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491453BDBM50491453(CHEMBL2381765)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491451BDBM50491451(CHEMBL2381769)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50491450BDBM50491450(CHEMBL2381772)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at recombinant human adenosine A2A receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP production after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed