Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50005314
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50490935(d4TTP-4PEG-TMC | CHEMBL2348625)
Affinity DataIC50: 3nMAssay Description:Competitive inhibition of C-Terminal histidine-tagged wild type heterodimeric HIV-1 reverse transcriptase p66/p51 assessed as inhibition of dTTP inco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50467347(CHEMBL72335)
Affinity DataIC50: 9nMAssay Description:Competitive inhibition of C-Terminal histidine-tagged wild type heterodimeric HIV-1 reverse transcriptase p66/p51 assessed as inhibition of dGTP inco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50467347(CHEMBL72335)
Affinity DataIC50: 13nMAssay Description:Competitive inhibition of C-Terminal histidine-tagged wild type heterodimeric HIV-1 reverse transcriptase p66/p51 assessed as inhibition of dTTP inco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50490935(d4TTP-4PEG-TMC | CHEMBL2348625)
Affinity DataIC50: 42nMAssay Description:Competitive inhibition of C-Terminal histidine-tagged wild type heterodimeric HIV-1 reverse transcriptase p66/p51 assessed as inhibition of dGTP inco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50490936(CHEMBL2348624)
Affinity DataIC50: 64nMAssay Description:Competitive inhibition of C-Terminal histidine-tagged wild type heterodimeric HIV-1 reverse transcriptase p66/p51 assessed as inhibition of dGTP inco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50490936(CHEMBL2348624)
Affinity DataIC50: 122nMAssay Description:Competitive inhibition of C-Terminal histidine-tagged wild type heterodimeric HIV-1 reverse transcriptase p66/p51 assessed as inhibition of dTTP inco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50370655(CHEMBL485652)
Affinity DataIC50: 1.30E+4nMAssay Description:Competitive inhibition of C-Terminal histidine-tagged wild type heterodimeric HIV-1 reverse transcriptase p66/p51 assessed as inhibition of dTTP inco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)