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Found 4 Enz. Inhib. hit(s) with all data for entry = 50005461
TargetHistone deacetylase(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of HDAC isolated from human HeLa cell nuclear extract after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50492268(CHEMBL2398772)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of HDAC isolated from human HeLa cell nuclear extract after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50492268(CHEMBL2398772)
Affinity DataEC50:  20nMAssay Description:Transactivation of human RXRalpha transfected in human 293 cells after 48 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataEC50:  149nMAssay Description:Transactivation of human RXRalpha transfected in human 293 cells after 48 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair