Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50043124
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100750BDBM100750(CHEMBL2397003 | US8507714, 239)
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210730BDBM50210730(4-((R)-1-((R)-6-(5-chloro-2-methoxybenzyl)-2,5-dio...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436400BDBM50436400(CHEMBL2397008)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436403BDBM50436403(CHEMBL2397001)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436399BDBM50436399(CHEMBL2397009)
Affinity DataIC50: 410nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436419BDBM50436419(CHEMBL2397011)
Affinity DataIC50: 520nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436398BDBM50436398(CHEMBL2396929)
Affinity DataIC50: 570nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436404BDBM50436404(CHEMBL2397000)
Affinity DataIC50: 570nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436397BDBM50436397(CHEMBL2396997)
Affinity DataIC50: 660nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436405BDBM50436405(CHEMBL2396999)
Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436407BDBM50436407(CHEMBL2396996)
Affinity DataIC50: 770nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436406BDBM50436406(CHEMBL2396998)
Affinity DataIC50: 790nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436402BDBM50436402(CHEMBL2397002)
Affinity DataIC50: 850nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436422BDBM50436422(CHEMBL2397006)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436420BDBM50436420(CHEMBL2397010)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100747BDBM100747(CHEMBL2397007 | US8507714, 151)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436412BDBM50436412(CHEMBL2396924)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436417BDBM50436417(CHEMBL2396919)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436409BDBM50436409(CHEMBL2396927)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436414BDBM50436414(CHEMBL2396922)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436418BDBM50436418(CHEMBL2397012)
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436411BDBM50436411(CHEMBL2396925)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436413BDBM50436413(CHEMBL2396923)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436410BDBM50436410(CHEMBL2396926)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436408BDBM50436408(CHEMBL2396928)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436401BDBM50436401(CHEMBL2397005)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436415BDBM50436415(CHEMBL2396921)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436416BDBM50436416(CHEMBL2396920)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCathepsin G(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436400BDBM50436400(CHEMBL2397008)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human neutrophil cathepsin G using Boc-Gln-Ala-Arg-MCA as substrate preincubated for 10 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCathepsin G(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436398BDBM50436398(CHEMBL2396929)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human neutrophil cathepsin G using Boc-Gln-Ala-Arg-MCA as substrate preincubated for 10 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436401BDBM50436401(CHEMBL2397005)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human recombinant chymase using Suc-Ala-Ala-Pro-Phe-MCA as substrate assessed as AMC formation preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436398BDBM50436398(CHEMBL2396929)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-Ala-Ala-Pro-Val-pNA as substrate preincubated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436397BDBM50436397(CHEMBL2396997)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-Ala-Ala-Pro-Val-pNA as substrate preincubated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCathepsin G(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436397BDBM50436397(CHEMBL2396997)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human neutrophil cathepsin G using Boc-Gln-Ala-Arg-MCA as substrate preincubated for 10 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCathepsin G(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100750BDBM100750(CHEMBL2397003 | US8507714, 239)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human neutrophil cathepsin G using Boc-Gln-Ala-Arg-MCA as substrate preincubated for 10 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 100750BDBM100750(CHEMBL2397003 | US8507714, 239)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-Ala-Ala-Pro-Val-pNA as substrate preincubated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCathepsin G(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210730BDBM50210730(4-((R)-1-((R)-6-(5-chloro-2-methoxybenzyl)-2,5-dio...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human neutrophil cathepsin G using Boc-Gln-Ala-Arg-MCA as substrate preincubated for 10 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCathepsin G(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436399BDBM50436399(CHEMBL2397009)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human neutrophil cathepsin G using Boc-Gln-Ala-Arg-MCA as substrate preincubated for 10 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436400BDBM50436400(CHEMBL2397008)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-Ala-Ala-Pro-Val-pNA as substrate preincubated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436399BDBM50436399(CHEMBL2397009)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-Ala-Ala-Pro-Val-pNA as substrate preincubated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Asubio Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210730BDBM50210730(4-((R)-1-((R)-6-(5-chloro-2-methoxybenzyl)-2,5-dio...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-Ala-Ala-Pro-Val-pNA as substrate preincubated for 10 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed