Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50006051
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50396023(CHEMBL2169919)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human recombinant DOT1L (catalytic domain 1 to 472) using [3H]-SAM by scintillation containingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50396980(CHEMBL2171169)
Affinity DataKi:  0.720nMAssay Description:Inhibition of human recombinant DOT1L (catalytic domain 1 to 472) using [3H]-SAM by scintillation containingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50443018(CHEMBL3087503)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human recombinant DOT1L (catalytic domain 1 to 472) using [3H]-SAM by scintillation containingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50443019(CHEMBL3087502)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human recombinant DOT1L (catalytic domain 1 to 472) using [3H]-SAM by scintillation containingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50396981(CHEMBL2171174)
Affinity DataKi:  290nMAssay Description:Inhibition of human recombinant DOT1L (catalytic domain 1 to 472) using [3H]-SAM by scintillation containingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-arginine methyltransferase CARM1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50443018(CHEMBL3087503)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SUV39H1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50443019(CHEMBL3087502)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of SUV39H1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50396980(CHEMBL2171169)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50443020(CHEMBL3087501)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human recombinant DOT1L (catalytic domain 1 to 472) using [3H]-SAM by scintillation containingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50396980(CHEMBL2171169)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50443020(CHEMBL3087501)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50443018(CHEMBL3087503)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50443020(CHEMBL3087501)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50443019(CHEMBL3087502)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of CARM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SUV39H1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50396980(CHEMBL2171169)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of SUV39H1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SUV39H1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50443018(CHEMBL3087503)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of SUV39H1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SUV39H1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50443020(CHEMBL3087501)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of SUV39H1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50443019(CHEMBL3087502)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of PRMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed