Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50043278
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438582BDBM50438582(CHEMBL2413849)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438582BDBM50438582(CHEMBL2413849)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human 17beta-HSD5 expressed in human CWR22R cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438585BDBM50438585(CHEMBL2413850)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438594BDBM50438594(CHEMBL2413860)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438586BDBM50438586(CHEMBL2413851)
Affinity DataIC50: 12nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438587BDBM50438587(CHEMBL2413852)
Affinity DataIC50: 13nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438582BDBM50438582(CHEMBL2413849)
Affinity DataIC50: 24nMAssay Description:Inhibition of human AKR1C3-mediated 9,10-phenanthrenequinone reduction after 10 to 20 mins by spectrophotometry in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438588BDBM50438588(CHEMBL2413853)
Affinity DataIC50: 33nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438583BDBM50438583(CHEMBL2413863)
Affinity DataIC50: 37nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438583BDBM50438583(CHEMBL2413863)
Affinity DataIC50: 58nMAssay Description:Inhibition of human 17beta-HSD5 expressed in human CWR22R cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438590BDBM50438590(CHEMBL2413855)
Affinity DataIC50: 140nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438596BDBM50438596(CHEMBL2413861)
Affinity DataIC50: 160nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438592BDBM50438592(CHEMBL2413857)
Affinity DataIC50: 230nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438595BDBM50438595(CHEMBL2413859)
Affinity DataIC50: 770nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438597BDBM50438597(CHEMBL2413864)
Affinity DataIC50: 790nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438591BDBM50438591(CHEMBL2413856)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438589BDBM50438589(CHEMBL2413854)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438593BDBM50438593(CHEMBL2413858)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438598BDBM50438598(CHEMBL2413862)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C3(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438584BDBM50438584(CHEMBL2413848)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 17beta-HSD5 expressed in HEK293 cells using androstenedione as substrate assessed as testosterone synthesis after 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438582BDBM50438582(CHEMBL2413849)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human AKR1C2-mediated 9,10-phenanthrenequinone reduction after 10 to 20 mins by spectrophotometry in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438582BDBM50438582(CHEMBL2413849)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438582BDBM50438582(CHEMBL2413849)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438582BDBM50438582(CHEMBL2413849)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Astellas Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438582BDBM50438582(CHEMBL2413849)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed