Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50005541
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492703BDBM50492703(CHEMBL2408158)
Affinity DataIC50: 53nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492718BDBM50492718(CHEMBL2408008)
Affinity DataIC50: 60nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492724BDBM50492724(CHEMBL2408176)
Affinity DataIC50: 77nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492705BDBM50492705(CHEMBL2408007)
Affinity DataIC50: 90nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492726BDBM50492726(CHEMBL2408161)
Affinity DataIC50: 108nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492704BDBM50492704(CHEMBL2408152)
Affinity DataIC50: 262nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492721BDBM50492721(CHEMBL2408183)
Affinity DataIC50: 316nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492733BDBM50492733(CHEMBL2408193)
Affinity DataIC50: 364nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492720BDBM50492720(CHEMBL2408157)
Affinity DataIC50: 390nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492731BDBM50492731(CHEMBL2408170)
Affinity DataIC50: 669nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492716BDBM50492716(CHEMBL2408168)
Affinity DataIC50: 675nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492707BDBM50492707(CHEMBL2407102)
Affinity DataIC50: 769nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492714BDBM50492714(CHEMBL2408172)
Affinity DataIC50: 1.24E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492717BDBM50492717(CHEMBL2408165)
Affinity DataIC50: 1.29E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492719BDBM50492719(CHEMBL2408173)
Affinity DataIC50: 1.52E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492708BDBM50492708(CHEMBL2408184)
Affinity DataIC50: 1.55E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492729BDBM50492729(CHEMBL2408180)
Affinity DataIC50: 1.57E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492723BDBM50492723(CHEMBL2408192)
Affinity DataIC50: 1.61E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492702BDBM50492702(CHEMBL2408159)
Affinity DataIC50: 1.81E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492713BDBM50492713(CHEMBL2408174)
Affinity DataIC50: 1.90E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492710BDBM50492710(CHEMBL2408181)
Affinity DataIC50: 2.50E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492732BDBM50492732(CHEMBL2408160)
Affinity DataIC50: 2.62E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492722BDBM50492722(CHEMBL2408175)
Affinity DataIC50: 2.65E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492715BDBM50492715(CHEMBL2408169)
Affinity DataIC50: 3.00E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492725BDBM50492725(CHEMBL2408167)
Affinity DataIC50: 3.08E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492712BDBM50492712(CHEMBL2408178)
Affinity DataIC50: 3.99E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492730BDBM50492730(CHEMBL2408177)
Affinity DataIC50: 4.23E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492711BDBM50492711(CHEMBL2408179)
Affinity DataIC50: 4.50E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492735BDBM50492735(CHEMBL2408156)
Affinity DataIC50: 4.74E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492700BDBM50492700(CHEMBL2408163)
Affinity DataIC50: 5.38E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492728BDBM50492728(CHEMBL2408186)
Affinity DataIC50: 5.90E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492701BDBM50492701(CHEMBL2408162)
Affinity DataIC50: 7.18E+3nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492709BDBM50492709(CHEMBL2408182)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492727BDBM50492727(CHEMBL2408197)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492706BDBM50492706(CHEMBL2408198)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Addex Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50492734BDBM50492734(CHEMBL2408171)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed