Compile Data Set for Download or QSAR
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Found 16 Enz. Inhib. hit(s) with all data for entry = 50001490
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50228778(4,4''-Dihydroxyoctafluoroazobenzene | CHEMBL79036)
Affinity DataKi:  4.00E+3nMpH: 7.4Assay Description:Binding constant of Testosterone-5 alpha-reductase activity at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015844(2,3,5,6-Tetrafluoro-4-pentafluorophenylazo-phenol ...)
Affinity DataKi:  1.00E+4nMpH: 7.4Assay Description:Inhibition of Steroid 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50228778(4,4''-Dihydroxyoctafluoroazobenzene | CHEMBL79036)
Affinity DataIC50:  790nMpH: 6.6Assay Description:Inhibition of 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataIC50:  1.60E+3nMpH: 6.6Assay Description:Inhibition of rat testosterone-5 alpha-reductase activity at pH 6.6 from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015844(2,3,5,6-Tetrafluoro-4-pentafluorophenylazo-phenol ...)
Affinity DataIC50:  2.00E+3nMpH: 6.6Assay Description:Inhibition of rat testosterone-5 alpha-reductase activity at pH 6.6 from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataIC50:  2.60E+3nMpH: 7.4Assay Description:Inhibition of Testosterone-5 alpha-reductase activity at pH 7.4 from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50228778(4,4''-Dihydroxyoctafluoroazobenzene | CHEMBL79036)
Affinity DataIC50:  5.00E+3nMpH: 7.4Assay Description:Inhibition of Testosterone-5 alpha-reductase activity at pH 7.4 from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of Steroid 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015844(2,3,5,6-Tetrafluoro-4-pentafluorophenylazo-phenol ...)
Affinity DataIC50:  1.40E+4nMpH: 7.4Assay Description:Inhibition of Testosterone-5 alpha-reductase activity at pH 7.4 from ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015846(1,2,3,4,6,7,8,9-Octafluoro-5,11-dihydro-10-oxa-5,1...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Steroid 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015844(2,3,5,6-Tetrafluoro-4-pentafluorophenylazo-phenol ...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015844(2,3,5,6-Tetrafluoro-4-pentafluorophenylazo-phenol ...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015846(1,2,3,4,6,7,8,9-Octafluoro-5,11-dihydro-10-oxa-5,1...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015843(2,3,4,5-Tetrafluoro-6-pentafluorophenylazo-phenol ...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of Steroid 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50015843(2,3,4,5-Tetrafluoro-6-pentafluorophenylazo-phenol ...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of 17-alpha-hydroxylase/17,20 lyase from rat testes microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed