Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50048846
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318494BDBM50318494(3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,...)
Affinity DataIC50: 1nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228791BDBM50228791(CHEMBL329897)
Affinity DataIC50: 1.5nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228797BDBM50228797(CHEMBL89260)
Affinity DataIC50: 1.70nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228807BDBM50228807(CHEMBL2092901)
Affinity DataIC50: 2nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228801BDBM50228801(CHEMBL89049)
Affinity DataIC50: 2.60nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228811BDBM50228811(CHEMBL84906)
Affinity DataIC50: 2.70nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228808BDBM50228808(CHEMBL86415)
Affinity DataIC50: 3.10nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228810BDBM50228810(CHEMBL89904)
Affinity DataIC50: 3.60nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50227246BDBM50227246(CHEMBL3392282)
Affinity DataIC50: 4nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228804BDBM50228804(CHEMBL89175)
Affinity DataIC50: 5.20nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228812BDBM50228812(CHEMBL315125)
Affinity DataIC50: 11nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228796BDBM50228796(CHEMBL330707)
Affinity DataIC50: 14nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228795BDBM50228795(CHEMBL315298)
Affinity DataIC50: 17nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228790BDBM50228790(CHEMBL440695)
Affinity DataIC50: 17nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228805BDBM50228805(CHEMBL87921)
Affinity DataIC50: 26nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50227344BDBM50227344(CHEMBL3392280)
Affinity DataIC50: 26nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228806BDBM50228806(CHEMBL261982)
Affinity DataIC50: 50nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228799BDBM50228799(CHEMBL313446)
Affinity DataIC50: 88nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228792BDBM50228792(CHEMBL88191)
Affinity DataIC50: 100nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015432BDBM50015432(CHEMBL39925 | 6-Methyl-2-methylsulfanyl-4-(3-nitro...)
Affinity DataIC50: 130nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228793BDBM50228793(CHEMBL89174)
Affinity DataIC50: 140nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228802BDBM50228802(CHEMBL89256)
Affinity DataIC50: 160nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228809BDBM50228809(CHEMBL88449)
Affinity DataIC50: 270nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228794BDBM50228794(CHEMBL315839)
Affinity DataIC50: 280nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226804BDBM50226804(CHEMBL88149)
Affinity DataIC50: 710nMAssay Description:In vitro vasorelaxant activity (calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Human)
Squibb Institute For Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228803BDBM50228803(CHEMBL1907867)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro vasorelaxant activity (voltage-gated calcium channel blocking activity) was determined with potassium-depolarized rabbit thoracic aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed