Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50044279
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50438936(CHEMBL2420629 | GNE-617)
Affinity DataEC50:  1.10nMAssay Description:Inhibition of NAMPT in human PC3 cells assessed as reduction in NAD level after 48 hrs by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011266(CHEMBL3260358)
Affinity DataEC50:  1.20nMAssay Description:Inhibition of NAMPT in human PC3 cells assessed as reduction in NAD level after 48 hrs by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50438936(CHEMBL2420629 | GNE-617)
Affinity DataEC50:  1.30nMAssay Description:Inhibition of NAMPT in mouse cells assessed as reduction in NAD level after 48 hrs by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011259(CHEMBL3260362)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50438936(CHEMBL2420629 | GNE-617)
Affinity DataIC50: 5nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011266(CHEMBL3260358)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011267(CHEMBL3260359)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011268(CHEMBL3260357)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011269(CHEMBL3260364)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011271(CHEMBL3260360)
Affinity DataIC50: 10nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011272(CHEMBL3260366)
Affinity DataIC50: 10nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011273(CHEMBL3260361)
Affinity DataIC50: 11nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011274(CHEMBL3260363)
Affinity DataIC50: 12nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50438966(CHEMBL2420667)
Affinity DataIC50: 18nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Rat)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50438936(CHEMBL2420629 | GNE-617)
Affinity DataIC50: 23nMAssay Description:Inhibition of rat NAMPT after 30 mins by mass spectrometry-based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50438936(CHEMBL2420629 | GNE-617)
Affinity DataIC50: 24nMAssay Description:Inhibition of mouse NAMPT after 30 mins by mass spectrometry-based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50438967(CHEMBL2420666)
Affinity DataIC50: 28nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Rat)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011266(CHEMBL3260358)
Affinity DataIC50: 35nMAssay Description:Inhibition of rat NAMPT after 30 mins by mass spectrometry-based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011275(CHEMBL3260347)
Affinity DataIC50: 54nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011266(CHEMBL3260358)
Affinity DataIC50: 59nMAssay Description:Inhibition of mouse NAMPT after 30 mins by mass spectrometry-based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Mouse)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011266(CHEMBL3260358)
Affinity DataEC50:  70nMAssay Description:Inhibition of NAMPT in mouse cells assessed as reduction in NAD level after 48 hrs by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011276(CHEMBL3260367)
Affinity DataIC50: 99nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011277(CHEMBL3260346)
Affinity DataIC50: 100nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011278(CHEMBL3260356 | US10696692, Example 269)
Affinity DataIC50: 110nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011279(CHEMBL3260365)
Affinity DataIC50: 190nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011280(CHEMBL3260353 | US10696692, Example 156)
Affinity DataIC50: 300nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011281(CHEMBL3260355 | US10696692, Example 9)
Affinity DataIC50: 370nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011282(CHEMBL3259825)
Affinity DataIC50: 390nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011283(CHEMBL3260351)
Affinity DataIC50: 400nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011284(CHEMBL3260350)
Affinity DataIC50: 410nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011285(CHEMBL3260352 | US10696692, Example 30)
Affinity DataIC50: 410nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011286(CHEMBL3260354 | US10696692, Example 117)
Affinity DataIC50: 440nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011287(CHEMBL3260344)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011288(CHEMBL3260348)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011289(CHEMBL3260349)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011290(CHEMBL3260343)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50011291(CHEMBL3260345)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of C-terminal His-6-tagged full length human NAMPT expressed in Escherichia coli (DE3) cells after 30 mins by mass spectrometry-based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed