Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50042451
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426366BDBM50426366(CHEMBL2326408)
Affinity DataIC50: 51nMAssay Description:Displacement of fluorescein-labeled 25-hydroxycholesterol from human RORgammat LBD (262-518) Escherichia coli BL21(DE3) after 6 hrs by fluorescence p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426366BDBM50426366(CHEMBL2326408)
Affinity DataIC50: 51nMAssay Description:Displacement of fluorescein-labeled 25-hydroxycholesterol from human RORgammat LBD (262-518) Escherichia coli BL21(DE3) after 6 hrs by fluorescence p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426366BDBM50426366(CHEMBL2326408)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in HEK293t cells co-expressing Gal4-DNA binding domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426370BDBM50426370(CHEMBL2326414)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426372BDBM50426372(CHEMBL2326412)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426377BDBM50426377(CHEMBL2326703)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426367BDBM50426367(CHEMBL2326416)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426371BDBM50426371(CHEMBL2326413)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426366BDBM50426366(CHEMBL2326408)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426369BDBM50426369(CHEMBL2326415)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 46355BDBM46355(MLS000069819 | cid_2724385 | SMR000059217 | DIGOXI...)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426368BDBM50426368(CHEMBL1370683)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426387BDBM50426387(CHEMBL1337164)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426376BDBM50426376(CHEMBL2326409)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426373BDBM50426373(CHEMBL2321922)
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426366BDBM50426366(CHEMBL2326408)
Affinity DataIC50: 4.50E+3nMAssay Description:Antagonist activity at TRalpha (unknown origin) expressed in HEK293t cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426378BDBM50426378(CHEMBL2326702)
Affinity DataIC50: 4.70E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426374BDBM50426374(CHEMBL2326411)
Affinity DataIC50: 6.60E+3nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426366BDBM50426366(CHEMBL2326408)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at LXRalpha (unknown origin) expressed in HEK293t cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426379BDBM50426379(CHEMBL2326701)
Affinity DataIC50: 1.28E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426366BDBM50426366(CHEMBL2326408)
Affinity DataIC50: 1.30E+4nMAssay Description:Antagonist activity at TRbeta (unknown origin) expressed in HEK293t cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426366BDBM50426366(CHEMBL2326408)
Affinity DataIC50: 1.40E+4nMAssay Description:Antagonist activity at ERRalpha (unknown origin) expressed in HEK293t cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426385BDBM50426385(CHEMBL1518643)
Affinity DataIC50: 1.57E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426384BDBM50426384(CHEMBL2326697)
Affinity DataIC50: 2.25E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426380BDBM50426380(CHEMBL2326700)
Affinity DataIC50: 2.44E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426382BDBM50426382(CHEMBL2326698)
Affinity DataIC50: 2.90E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426375BDBM50426375(CHEMBL2326410)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426383BDBM50426383(CHEMBL1445011)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426386BDBM50426386(CHEMBL1879167)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
New York University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50426381BDBM50426381(CHEMBL2326699)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at transactivation domain of RORgammat (unknown origin) expressed in Drosophila Schneider cells co-expressing Gal4-DNA binding do...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed