Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with all data for entry = 50043472
TargetCytochrome P450 2D6(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50441620(CHEMBL2437199)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as dextromethorphan O-demethylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50441621(CHEMBL2437330)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as dextromethorphan O-demethylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50441621(CHEMBL2437330)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes assessed as ethoxyresorufin O-deethylation after 20 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50441621(CHEMBL2437330)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as tolbutamide hydroxylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50441620(CHEMBL2437199)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes assessed as ethoxyresorufin O-deethylation after 20 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50441620(CHEMBL2437199)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as tolbutamide hydroxylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed