Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 6088
TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108055(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50: 12nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108055(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50: 22nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108053(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50: 25nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108051(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50: 29nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108050(4-((4-((2,3-dimethyl-2H-indazole-6-yl)amino) pyrim...)
Affinity DataIC50: 34nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM26474(GW-786034 | JMC514632 Compound 13 | 5-({4-[(2,3-di...)
Affinity DataIC50: 43nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108053(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50: 62nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108051(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50: 120nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108054(4-((4-((2,3-dimethyl-2H-indazole-6-yl)amino) pyrim...)
Affinity DataIC50: 120nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108052(4-((4-((2,3-dimethyl-2H-indazole-6-yl)amino) pyrim...)
Affinity DataIC50: 160nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108052(4-((4-((2,3-dimethyl-2H-indazole-6-yl)amino) pyrim...)
Affinity DataIC50: 280nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108057(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50: 320nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108054(4-((4-((2,3-dimethyl-2H-indazole-6-yl)amino) pyrim...)
Affinity DataIC50: 360nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108059(N-carbamimidoyl-4-((4-((2,3-dimethyl-2H-indazole- ...)
Affinity DataIC50: 360nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108050(4-((4-((2,3-dimethyl-2H-indazole-6-yl)amino) pyrim...)
Affinity DataIC50: 460nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM26474(GW-786034 | JMC514632 Compound 13 | 5-({4-[(2,3-di...)
Affinity DataIC50: 620nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108057(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50: 650nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108059(N-carbamimidoyl-4-((4-((2,3-dimethyl-2H-indazole- ...)
Affinity DataIC50: 720nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108049(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50: 870nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108058(N-carbamimidoyl-4-((4-((2,3-dimethyl-2H-indazole- ...)
Affinity DataIC50: 930nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108058(N-carbamimidoyl-4-((4-((2,3-dimethyl-2H-indazole- ...)
Affinity DataIC50: 1.34E+3nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108049(4-((4-((2,3-dimethyl-2H-indazole-6-yl)(methyl) ami...)
Affinity DataIC50: 1.35E+3nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetReceptor protein-tyrosine kinase(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108059(N-carbamimidoyl-4-((4-((2,3-dimethyl-2H-indazole- ...)
Affinity DataIC50: 1.37E+3nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108056(4-((4-((2,3-dimethyl-2H-indazole-6-yl)amino) pyrim...)
Affinity DataIC50: 1.63E+3nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM108056(4-((4-((2,3-dimethyl-2H-indazole-6-yl)amino) pyrim...)
Affinity DataIC50: 2.18E+3nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed
TargetReceptor protein-tyrosine kinase(Human)
Shandong Institute of Pharmaceutical Industry

LigandPNGBDBM26474(GW-786034 | JMC514632 Compound 13 | 5-({4-[(2,3-di...)
Affinity DataIC50: 5.95E+3nMT: 2°CAssay Description:To the assay kit, 2.5 µL of different concentrate of the test compounds, Pazopanib or water (control) were added and incubated for 1 h at room t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2014
Entry Details Article
PubMed