Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50043569
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443088BDBM50443088(CHEMBL3087216)
Affinity DataIC50: 27nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443089BDBM50443089(CHEMBL3086715)
Affinity DataIC50: 28nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443089BDBM50443089(CHEMBL3086715)
Affinity DataIC50: 28.4nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443090BDBM50443090(CHEMBL3086712)
Affinity DataIC50: 37nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443091BDBM50443091(CHEMBL3087511)
Affinity DataIC50: 47nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443092BDBM50443092(CHEMBL3085792)
Affinity DataIC50: 48nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443093BDBM50443093(CHEMBL3087217)
Affinity DataIC50: 51nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443087BDBM50443087(CHEMBL3087214)
Affinity DataIC50: 61nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443086BDBM50443086(CHEMBL3087508)
Affinity DataIC50: 65nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443085BDBM50443085(Mavoglurant | AFQ056)
Affinity DataIC50: 72nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443084BDBM50443084(CHEMBL3087220)
Affinity DataIC50: 72nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443083BDBM50443083(CHEMBL3087219)
Affinity DataIC50: 76nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443082BDBM50443082(CHEMBL3087513)
Affinity DataIC50: 85nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443081BDBM50443081(CHEMBL3087212)
Affinity DataIC50: 86nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443080BDBM50443080(CHEMBL3087514)
Affinity DataIC50: 103nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443080BDBM50443080(CHEMBL3087514)
Affinity DataIC50: 103nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443079BDBM50443079(CHEMBL3087225)
Affinity DataIC50: 132nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443078BDBM50443078(CHEMBL3087509)
Affinity DataIC50: 137nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443077BDBM50443077(CHEMBL3087505)
Affinity DataIC50: 168nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443076BDBM50443076(CHEMBL3087507)
Affinity DataIC50: 170nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443075BDBM50443075(CHEMBL3086717)
Affinity DataIC50: 180nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443074BDBM50443074(CHEMBL3087218)
Affinity DataIC50: 187nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443073BDBM50443073(CHEMBL3086716)
Affinity DataIC50: 189nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443072BDBM50443072(CHEMBL3087226)
Affinity DataIC50: 210nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443071BDBM50443071(CHEMBL3086718)
Affinity DataIC50: 227nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443070BDBM50443070(CHEMBL3087213)
Affinity DataIC50: 298nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443069BDBM50443069(CHEMBL3086719)
Affinity DataIC50: 306nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443068BDBM50443068(CHEMBL3087224)
Affinity DataIC50: 308nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443067BDBM50443067(CHEMBL3087211)
Affinity DataIC50: 340nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443066BDBM50443066(CHEMBL3087223)
Affinity DataIC50: 543nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443065BDBM50443065(CHEMBL3087506)
Affinity DataIC50: 575nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443064BDBM50443064(CHEMBL3086720)
Affinity DataIC50: 813nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443063BDBM50443063(CHEMBL3087221)
Affinity DataIC50: 818nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443062BDBM50443062(CHEMBL3086713)
Affinity DataIC50: 930nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443057BDBM50443057(CHEMBL3086714)
Affinity DataIC50: 1.01E+3nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443061BDBM50443061(CHEMBL3087510)
Affinity DataIC50: 1.02E+3nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443060BDBM50443060(CHEMBL3087215)
Affinity DataIC50: 2.19E+3nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443059BDBM50443059(CHEMBL3087512)
Affinity DataIC50: 3.35E+3nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443058BDBM50443058(CHEMBL3086711)
Affinity DataIC50: 8.60E+3nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merz Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443056BDBM50443056(CHEMBL3087222)
Affinity DataIC50: 1.00E+5nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed