Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50043627
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443803BDBM50443803(CHEMBL3094250)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443800BDBM50443800(CHEMBL3094255)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443805BDBM50443805(CHEMBL3094249)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81395BDBM81395(APO-866 | US20240327418, Example FK866 | US2024030...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443801BDBM50443801(CHEMBL3094254)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443798BDBM50443798(CHEMBL3094258)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443799BDBM50443799(CHEMBL3094257)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443796BDBM50443796(CHEMBL3094229)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443802BDBM50443802(CHEMBL3094251)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443793BDBM50443793(CHEMBL3094236)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443791BDBM50443791(CHEMBL3094238)
Affinity DataIC50: 12nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435350BDBM50435350(CHEMBL17289)
Affinity DataIC50: 18nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443797BDBM50443797(CHEMBL3094224)
Affinity DataIC50: 23nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443804BDBM50443804(CHEMBL2417795)
Affinity DataIC50: 39nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443794BDBM50443794(CHEMBL3094234)
Affinity DataIC50: 49nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443795BDBM50443795(CHEMBL3094230)
Affinity DataIC50: 50nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Topotarget

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50443792BDBM50443792(CHEMBL3094237)
Affinity DataIC50: 133nMAssay Description:Inhibition of NAMPT in human HepG2 cells using [14C]-nicotinamide/PRPP as substrate assessed as formation of [14C]-nicotinamide mononucleotide after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed