Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50043665
TargetCytochrome P450 2C8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444436(CHEMBL3092124)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes measured after concurrent incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444436(CHEMBL3092124)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes measured after compound pre-incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444436(CHEMBL3092124)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2CJ in human liver microsomes measured after compound pre-incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444436(CHEMBL3092124)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes measured after compound pre-incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444436(CHEMBL3092124)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes measured after compound pre-incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D4(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444436(CHEMBL3092124)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of rat CYP2D4 measured after concurrent incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444436(CHEMBL3092124)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2CJ in human liver microsomes measured after concurrent incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444436(CHEMBL3092124)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes measured after concurrent incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444436(CHEMBL3092124)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes measured after concurrent incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D4(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444436(CHEMBL3092124)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of rat CYP2D4 measured after compound pre-incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444436(CHEMBL3092124)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes measured after compound pre-incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444436(CHEMBL3092124)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes measured after concurrent incubationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed