Found 5 Enz. Inhib. hit(s) with all data for entry = 50005970 TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR using methylenetetrahydrofolate/dUMP as sustrate preincubated for 10 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR using methylenetetrahydrofolate/dUMP as sustrate preincubated for 10 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR by Michaelis-Menten plot analysis in presence of bovine serum albuminMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.42E+5nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR using methylenetetrahydrofolate/dUMP as sustrateMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR using methylenetetrahydrofolate/dUMP as sustrateMore data for this Ligand-Target Pair
