Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50022492
TargetTyrosine-protein kinase Mer(Human)
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 5nMAssay Description:Displacement of kinase tracer 236 from GST-tagged Mer (unknown origin) assessed as inhibition constant incubated for 1 hr by HTRF based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 8nMAssay Description:Displacement of kinase tracer 236 from GST-tagged Tyro3 (unknown origin) assessed as inhibition constant incubated for 1 hr by HTRF based TR-FRET ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataKd:  13nMAssay Description:Binding affinity to c-Met in human Hs-578T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataKd:  19nMAssay Description:Binding affinity to UFO in human Hs-578T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 29nMAssay Description:Displacement of kinase tracer 236 from GST-tagged Axl (unknown origin) assessed as inhibition constant incubated for 1 hr by HTRF based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 35nMAssay Description:Displacement of kinase tracer 236 from GST-tagged Met (unknown origin) assessed as inhibition constant incubated for 1 hr by HTRF based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAurora kinase B(Human)
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 36nMAssay Description:Displacement of kinase tracer 236 from GST-tagged Aurora B (unknown origin) assessed as inhibition constant incubated for 1 hr by HTRF based TR-FRET ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 51nMAssay Description:Displacement of kinase tracer 236 from GST-tagged LCK (unknown origin) assessed as inhibition constant incubated for 1 hr by HTRF based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Fer(Human)
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataKd:  107nMAssay Description:Binding affinity to FER in human Hs-578T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 5(Human)
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataKd:  124nMAssay Description:Binding affinity to MAP2K5 in human Hs-578T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataKd:  154nMAssay Description:Binding affinity to ABL1 in human Hs-578T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataKd:  217nMAssay Description:Binding affinity to SRC in human Hs-578T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 338nMAssay Description:Displacement of kinase tracer 236 from GST-tagged SRC (unknown origin) assessed as inhibition constant incubated for 1 hr by HTRF based TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Medical University Innsbruck

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 3.18E+3nMAssay Description:Displacement of kinase tracer 236 from GST-tagged CDK8 (unknown origin) assessed as inhibition constant incubated for 1 hr by HTRF based TR-FRET assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed